[Term]
id: PR:000027218
name: pTIRAP:PIP2:activated TLR4 complex (human)
def: "A TIRAP:PIP2:activated TLR4 complex in human in which the TIRAP/MAL component is phosphorylated." [TLR:AMM, PMID:12724322, PMID:18070880]
comment: Category=organism-complex. Requested by=TLR.
synonym: "pMal:activated TLR4 complex (human)" EXACT []
synonym: "pTIRAP:PIP2:MD2:LPS:TLR4 complex (human)" EXACT []
is_a: PR:000036078 ! TIRAP:PIP2:activated TLR4 complex
relationship: has_component CHEBI:16412 ! lipopolysaccharide
relationship: has_component CHEBI:18348 ! 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
relationship: has_component PR:000025787 ! Toll-like receptor 4 isoform 1, signal peptide removed N-glycosylated 1 (human)
relationship: has_component PR:000027214 ! Toll/interleukin-1 receptor domain-containing adapter protein isoform 1 phosphorylated 1 (human)
relationship: has_component PR:000025786 ! lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens