| PRO ID |
GO:0005680
Show OBO stanza
|
| PRO name |
anaphase-promoting complex |
| Synonyms |
| Other: |
EXACT: |
anaphase promoting complex |
|
| Definition |
A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B.
[GOC:jh, GOC:vw, PMID:10465783, PMID:10611969]
|
| Comment |
Note that the synonym 'APC' should not be confused with the abbreviation for the adenomatous polyposis coli gene and protein. |
| PRO Category |
|
| Parent |
GO:0031461 cullin-RING ubiquitin ligase complex |
| Term Hierarchy Visualization |
 DAG
 OLS
Cytoscape
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