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Protein Ontology Report - SCF ubiquitin ligase complex

GO:0019005 - http://purl.obolibrary.org/obo/GO_0019005
Ontology Information
PRO ID GO:0019005 Show OBO stanza
PRO name SCF ubiquitin ligase complex
Synonyms
Other: EXACT: CDL1 complex
Definition A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1). [PMID:15571813, PMID:15688063]
PRO Category
Parent GO:0031461 cullin-RING ubiquitin ligase complex
Term Hierarchy Visualization DAG     OLS     Cytoscape

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