PRO ID |
GO:0043514
Show OBO stanza
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PRO name |
interleukin-12 complex |
Synonyms |
Other: |
EXACT: |
IL-12 complex |
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Definition |
A protein complex that is composed of an interleukin-12 alpha (p35, product of the IL12A gene) and an interleukin-12 beta subunit (p40, product of the IL12B gene) and is secreted into the extracellular space.
[GOC:add, GOC:ebc, GOC:mah, PMID:12948519, PMID:1381512]
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Comment |
Note that this heterodimeric cytokine utilizes the IL-12p35 subunit as its alpha chain, which is also used by IL-35 as its alpha chain, and utilizes the IL-12p40 subunit as its beta chain, which is also used by IL-23 as its beta chain. |
PRO Category |
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Parent |
GO:0032991 protein-containing complex |
Term Hierarchy Visualization |
DAG
OLS
Cytoscape
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