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Protein Ontology Report - interleukin-12 complex

GO:0043514 -
Ontology Information
PRO ID GO:0043514 Show OBO stanza
PRO name interleukin-12 complex
Other: EXACT: IL-12 complex
Definition A protein complex that is composed of an interleukin-12 alpha (p35, product of the IL12A gene) and an interleukin-12 beta subunit (p40, product of the IL12B gene) and is secreted into the extracellular space. [GOC:add, GOC:ebc, GOC:mah, PMID:12948519, PMID:1381512]
Comment Note that this heterodimeric cytokine utilizes the IL-12p35 subunit as its alpha chain, which is also used by IL-35 as its alpha chain, and utilizes the IL-12p40 subunit as its beta chain, which is also used by IL-23 as its beta chain.
PRO Category
Parent GO:0032991 protein-containing complex
Term Hierarchy Visualization DAG     OLS     Cytoscape