| PRO ID |
GO:1990265
Show OBO stanza
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| PRO name |
platelet-derived growth factor complex |
| Synonyms |
| Other: |
RELATED: |
PDGF complex |
|
| Definition |
A protein complex consisting of two chains of platelet-derived growth factor (PDGF) subunits. PDGF dimers bind to PDGF receptors in the plasma membrane and induce receptor dimerisation and activation. PDGFs are involved in a wide variety of signalling processes. PDGFs are found in all vertebrates where at least 2 different chains (A and B) exist. In human (and other mammals), four types of PDGF chains (A, B, C, and D) are known which form five different dimers (AA, AB, BB, CC and DD).
[GOC:bhm, PMID:11331882]
|
| Comment |
An example of this is PDGFA in human (P04085) in PMID:20534510 (inferred from direct assay). |
| PRO Category |
|
| Parent |
GO:0032991 protein-containing complex |
| Term Hierarchy Visualization |
 DAG
 OLS
Cytoscape
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