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Protein Ontology Report - CHRD

PR:000000010 - http://purl.obolibrary.org/obo/PR_000000010
Ontology Information
PRO ID PR:000000010 Show OBO stanza / PAF
PRO name chordin
Synonyms
PRO-short-label: CHRD
Gene-based: UNQ217/PRO243
Definition A protein that is a translation product of the human CHRD gene or a 1:1 ortholog thereof. Chordin regulates signaling by BMP pathway. [PRO:CNA]
PRO Category gene
Parent PR:000000001 protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 6
sequence 4 organism-sequence 7
modification 3 organism-modification 3
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000036409
mCHRD/iso:1/SigPep-
capable_of GO:0008201 heparin binding PMID:15381701
capable_of GO:0005515 protein binding PMID:15381701
located_in GO:0005615 extracellular space PMID:15780974
participates_in GO:0001501 skeletal system development PMID:11784076
participates_in GO:0030514 negative regulation of BMP signaling pathway PMID:10479448, PMID:15780974
PR:000000087
CHRD/iso:2
has_part NOT Pfam:PF07452 CHRD domain
PR:000000010
CHRD
capable_of GO:0008201 heparin binding PIRSF:PIRSF002496
capable_of GO:0045545 syndecan binding PIRSF:PIRSF002496
capable_of GO:0005515 protein binding PIRSF:PIRSF002496
has_part Pfam:PF07452 CHRD domain PIRSF:PIRSF002496
has_part Pfam:PF00093 von Willebrand factor type C domain PIRSF:PIRSF002496
participates_in GO:0030510 regulation of BMP signaling pathway PIRSF:PIRSF002496
PR:000036410
frog-CHRD/iso:1/SigPep-
located_in GO:0005615 extracellular space PMID:8752213
part_of GO:0032991 protein-containing complex PMID:8752213
PR:000036411
mCHRD/iso:1/Clv:2
located_in GO:0005615 extracellular space PMID:10479448
participates_in GO:0001501 skeletal system development PMID:10479448
PR:Q9H2X0-1
hCHRD/iso:1
participates_in GO:0001501 skeletal system development PMID:9782094
PR:Q9H2X0-2
hCHRD/iso:2
participates_in NOT GO:0030514 negative regulation of BMP signaling pathway PMID:11472837
PR:Q9H2X0-4
hCHRD/iso:4
participates_in GO:0030514 negative regulation of BMP signaling pathway PMID:11472837
PR:Q9H2X0-5
hCHRD/iso:5
participates_in GO:0030514 negative regulation of BMP signaling pathway PMID:11472837
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0030514 negative regulation of BMP signaling pathway PR:000036409 mCHRD/iso:1/SigPep-

PMID:10479448, PMID:15780974
PR:Q9H2X0-4 hCHRD/iso:4

PMID:11472837
PR:Q9H2X0-5 hCHRD/iso:5

PMID:11472837
NOT GO:0030514 negative regulation of BMP signaling pathway PR:Q9H2X0-2 hCHRD/iso:2

PMID:11472837
GO:0001501 skeletal system development PR:000036409 mCHRD/iso:1/SigPep-

PMID:11784076
PR:000036411 mCHRD/iso:1/Clv:2

PMID:10479448
PR:Q9H2X0-1 hCHRD/iso:1

PMID:9782094
GO:0030510 regulation of BMP signaling pathway PR:000000010 CHRD

PIRSF:PIRSF002496
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005615 extracellular space PR:000036409 mCHRD/iso:1/SigPep-

PMID:15780974
PR:000036410 frog-CHRD/iso:1/SigPep-

PMID:8752213
PR:000036411 mCHRD/iso:1/Clv:2

PMID:10479448

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