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Protein Ontology Report - hTGFBR2/var:S449F

PR:000000064 - http://purl.obolibrary.org/obo/PR_000000064
Ontology Information
PRO ID PR:000000064 Show OBO stanza / PAF / GPI
PRO name TGF-beta receptor type-2 sequence variant S449F (human)
Synonyms
PRO-short-label: EXACT: hTGFBR2/var:S449F
PRO-proteoform-std: NARROW: UniProtKB:P37173-1, Ser-449, CHEBI:29997
Other: EXACT: TGF-beta receptor type-2 sequence variant 8 (human)
Definition A TGF-beta receptor type-2 (human) that has a Phe residue at the position equivalent to Ser-449 of the amino acid sequence represented by UniProtKB:P37173-1. Example: UniProtKB:P37173-1, Ser-449, CHEBI:29997. [PMID:15235604, PRO:CNA, PRO:DAN]
PRO Category organism-sequence
Parent PR:P37173 TGF-beta receptor type-2 (human)
Taxon NCBITaxon:9606 Homo sapiens
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000000064
hTGFBR2/var:S449F
Ser-449, CHEBI:29997
associated_with_disease_progression DOID:0050466 Loeys-Dietz syndrome PMID:15235604
enables NOT GO:0005026 transforming growth factor beta receptor activity, type II PMID:15235604

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