PRO Term |
GO Annotation |
Evidence |
PR:P84022-1
hSMAD3/iso:1
|
acts_upstream_of_or_within |
GO:0007179 transforming growth factor beta receptor signaling pathway
|
PMID:8774881 |
enables |
GO:0005515 protein binding
with PR:000025959 hTGFBR1/iso:1/SigPep-/Phos:1
|
PMID:12154125 |
enables |
GO:0005515 protein binding
with PR:O95405-1 hZFYVE9/iso:1
|
PMID:12154125 |
located_in |
GO:0005737 cytoplasm
|
PMID:17074053 |
PR:000026333
hSMAD3/iso:1/Phos:1
Ser-423/Ser-425, MOD:00046
|
acts_upstream_of_or_within |
GO:0007179 transforming growth factor beta receptor signaling pathway
|
PMID:8774881, PMID:9380693 |
acts_upstream_of_or_within |
GO:0006366 transcription by RNA polymerase II
|
PMID:10823886 |
enables |
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
|
PMID:10823886, PMID:12943993 |
enables |
GO:0008134 transcription factor binding
|
PMID:15084259 |
enables |
GO:0046332 SMAD binding
with PR:Q13485 hSMAD4
|
PMID:15350224, PMID:9311995 |
located_in |
GO:0005634 nucleus
|
PMID:10846168, PMID:15280432 |
part_of |
GO:0005667 transcription factor complex
|
PMID:12374795 |
PR:000036558
mSMAD3/iso:1/Phos:1
Ser-423/Ser-425, MOD:00046
|
enables |
GO:0003700 DNA-binding transcription factor activity
|
PMID:10823886, PMID:12943993 |
enables |
GO:0003690 double-stranded DNA binding
|
PMID:15282343 |
enables |
GO:0008134 transcription factor binding
|
PMID:15464984, PMID:9702197 |
located_in |
GO:0005634 nucleus
|
PMID:12943993, PMID:15282343 |
part_of |
GO:0005667 transcription factor complex
|
PMID:9702197 |
PR:000036557
hSMAD3/iso:1/AcPhos:1
Lys-19, MOD:00064|Ser-423/Ser-425, MOD:00046
|
acts_upstream_of_or_within |
GO:0007179 transforming growth factor beta receptor signaling pathway
|
PMID:17074756 |
enables |
GO:0003700 DNA-binding transcription factor activity
|
PMID:17074756 |
located_in |
GO:0005634 nucleus
|
PMID:17074756 |
PR:Q8BUN5-1
mSMAD3/iso:1
|
acts_upstream_of_or_within |
GO:0007179 transforming growth factor beta receptor signaling pathway
|
PMID:12543979 |
enables |
GO:0005515 protein binding
with PR:000036434 mTGFBR1/iso:1/SigPep-/Phos:1
|
PMID:12154125 |
enables |
GO:0005515 protein binding
with PR:A2A8R0 mZFYVE9/iso:1
|
PMID:12154125 |
PR:000036561
mSMAD3/iso:1/Phos:3
Thr-179, MOD:00047|Ser-204/Ser-208/Ser-213, MOD:00046
|
enables |
NOT
GO:0003713 transcription coactivator activity
|
PMID:10197981 |
located_in |
GO:0005737 cytoplasm
|
PMID:10197981 |
PR:000036560
mSMAD3/iso:1/Phos:2
Thr-8/Thr-179, MOD:00047|Ser-213, MOD:00046
|
enables |
GO:0003700 DNA-binding transcription factor activity
decreased relative to PR:000036558 mSMAD3/iso:1/Phos:1
|
PMID:15241418 |
|