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Protein Ontology Report - fam:TRPV

PR:000000681 - http://purl.obolibrary.org/obo/PR_000000681
Ontology Information
PRO ID PR:000000681 Show OBO stanza
PRO name transient receptor potential cation channel TRPV
Synonyms
PRO-short-label: EXACT: fam:TRPV
Definition A transient receptor potential channel protein that is a member of the subfamily V of the transient receptor potential cation channels (TRPs), with amino- and carboxyl-terminal intracellular domains separated by a domain (common with other ion channels) containing six transmembrane helices (S1-S6) in which the last two helices (S5 and S6) flank a loop, called the pore loop, which determines ion selectivity. The amino-terminal domain contains up to 6 copies of detectable ankyrin repeat (Pfam:PF00023). Most TRPs are relatively non-selective. They may be modulated by voltage changes but channel gating is generally effected by other means. [PMID:16382100, PMID:16460286, PMID:17579562, PRO:WCB]
PRO Category family
Parent PR:000044657 transient receptor potential channel protein
Term Hierarchy Visualization DAG     OLS     Cytoscape


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