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Protein Ontology Report - KCNA2

PR:000000810 - http://purl.obolibrary.org/obo/PR_000000810
Ontology Information
PRO ID PR:000000810 Show OBO stanza / PAF
PRO name voltage-gated potassium channel subunit KCNA2
Synonyms
PRO-short-label: KCNA2
EXACT: NGK1; voltage-gated K(+) channel HuKIV; voltage-gated potassium channel HBK5; voltage-gated potassium channel subunit Kv1.2
RELATED: MK2
Definition A shaker-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCNA2 gene or a 1:1 ortholog thereof. The Kv1.2 channel is involved in maintaining membrane potential, modulating electrical excitability in neurons and muscle. It can coassemble with other Kv1 subunits. [PMID:16382104]
PRO Category gene
Parent PR:000000709 shaker-related voltage-gated potassium channel alpha subunit
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 3
sequence 1 organism-sequence 4
modification 3 organism-modification 4
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:P16389-1
hKCNA2/iso:1
capable_of GO:0005251 delayed rectifier potassium channel activity PMID:1715584
located_in GO:0009986 cell surface PMID:15215309
part_of GO:0008076 voltage-gated potassium channel complex PMID:2251283
PR:000036587
hKCNA2/iso:1/Phos:2
Ser-440/Ser-441, MOD:00046
located_in GO:0009986 cell surface PMID:18056633
part_of GO:0008076 voltage-gated potassium channel complex PMID:18056633
PR:000036584
hKCNA2/iso:1/Phos:1
Tyr-132, MOD:00048
capable_of NOT GO:0005251 delayed rectifier potassium channel activity PMID:15215309
located_in GO:0044440 endosomal part PMID:15215309
PR:000036585
mKCNA2/iso:1/Phos:2
Ser-440/Ser-441, MOD:00046
located_in GO:0009986 cell surface PMID:18056633
part_of GO:0008076 voltage-gated potassium channel complex PMID:18056633
PR:000036586
rKCNA2/iso:1/Phos:2
Ser-440/Ser-441, MOD:00046
located_in GO:0009986 cell surface PMID:18056633
part_of GO:0008076 voltage-gated potassium channel complex PMID:18056633
PR:P63142-1
rKCNA2/iso:1
capable_of GO:0005515 protein binding with PR:P78352 hDLG4 PMID:17959782
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0009986 cell surface PR:000036585 mKCNA2/iso:1/Phos:2
Ser-440/Ser-441, MOD:00046
PMID:18056633
PR:000036586 rKCNA2/iso:1/Phos:2
Ser-440/Ser-441, MOD:00046
PMID:18056633
PR:000036587 hKCNA2/iso:1/Phos:2
Ser-440/Ser-441, MOD:00046
PMID:18056633
PR:P16389-1 hKCNA2/iso:1

PMID:15215309
GO:0044440 endosomal part PR:000036584 hKCNA2/iso:1/Phos:1
Tyr-132, MOD:00048
PMID:15215309

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