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Protein Ontology Report - IL1A

PR:000001135 - http://purl.obolibrary.org/obo/PR_000001135
Ontology Information
PRO ID PR:000001135 Show OBO stanza / PAF
PRO name interleukin-1 alpha
Synonyms
PRO-short-label: IL1A
EXACT: IL-1 alpha; hematopoietin-1
Gene-based: IL1F1
Definition An interleukin-1 that is a translation product of the human IL1A gene or a 1:1 ortholog thereof. Critical mediator of the immune and inflammatory responses. [PRO:CNA, Wikipedia:Interleukin_1]
PRO Category gene
Parent PR:000001091 interleukin-1
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 3
sequence 1 organism-sequence 2
modification 7 organism-modification 6
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000036599
hIL1A/iso:1/Myr:2
Lys-82, MOD:00087
located_in GO:0044425 membrane part PMID:8346241
PR:000036598
hIL1A/iso:1/Myr:1
Lys-83, MOD:00087
located_in GO:0044425 membrane part PMID:8346241
PR:000036597
hIL1A/iso:1/Clv:1
has_part NOT Pfam:PF02394 Interleukin-1 propeptide PMID:3281727
located_in GO:0005615 extracellular space PMID:3281727
PR:000036600
mIL1A/iso:1/Phos:1
Ser-90, MOD:00046
located_in GO:0044425 membrane part PMID:3126184
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0044425 membrane part PR:000036598 hIL1A/iso:1/Myr:1
Lys-83, MOD:00087
PMID:8346241
PR:000036599 hIL1A/iso:1/Myr:2
Lys-82, MOD:00087
PMID:8346241
PR:000036600 mIL1A/iso:1/Phos:1
Ser-90, MOD:00046
PMID:3126184
GO:0005615 extracellular space PR:000036597 hIL1A/iso:1/Clv:1

PMID:3281727

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