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Protein Ontology Report - IL1RN

PR:000001137 - http://purl.obolibrary.org/obo/PR_000001137
Ontology Information
PRO ID PR:000001137 Show OBO stanza / PAF
PRO name interleukin-1 receptor antagonist protein
Synonyms
PRO-short-label: EXACT: IL1RN
Gene-based: RELATED: IL1F3 | IL1RA
Other: EXACT: ICIL-1RA | IL-1RN | IL-1ra | IL1 inhibitor | IRAP | anakinra
Definition A protein that is a translation product of the human IL1RN gene or a 1:1 ortholog thereof. [PRO:CNA]
Comment Note: The active form inhibits the activity of IL-1 by binding to its receptor.
PRO Category gene
Parent PR:000000001 protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 3
sequence 4 organism-sequence 6
modification 3 organism-modification 1
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000036601
hIL1RN/iso:1/SigPep-
enables GO:0045352 interleukin-1 type I receptor antagonist activity PMID:2139180
located_in GO:0005615 extracellular space PMID:2139180
PR:P18510-4
hIL1RN/iso:4
located_in GO:0005622 intracellular anatomical structure PMID:12671514
PR:P18510-3
hIL1RN/iso:3
located_in GO:0005622 intracellular anatomical structure PMID:7629520
PR:P18510-2
hIL1RN/iso:2
located_in GO:0005622 intracellular anatomical structure PMID:1827201
located_in GO:0005615 extracellular space PMID:16564702
PR:P25085-2
mIL1RN/iso:2
located_in GO:0005615 extracellular space PMID:1524071
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005622 intracellular anatomical structure PR:P18510-2 hIL1RN/iso:2

PMID:1827201
PR:P18510-3 hIL1RN/iso:3

PMID:7629520
PR:P18510-4 hIL1RN/iso:4

PMID:12671514
GO:0005615 extracellular space PR:000036601 hIL1RN/iso:1/SigPep-

PMID:2139180
PR:P18510-2 hIL1RN/iso:2

PMID:16564702
PR:P25085-2 mIL1RN/iso:2

PMID:1524071

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