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Protein Ontology Report - CSF-1/PDGF receptor-type tyrosine-protein kinase

PR:000001810 - http://purl.obolibrary.org/obo/PR_000001810
Ontology Information
PRO ID PR:000001810 Show OBO stanza / PAF
PRO name CSF-1/PDGF receptor-type tyrosine-protein kinase
Definition A protein with core architecture consisting of asignal sequence, 5 Ig-like domains, followed by a transmembrane sequence, followed by a Protein tyrosine kinase domain (Pfam:PF07714). However, only 1-3 of the Ig domains are detected by the Pfam HMMs in most of the sequences. Pfam:PF00047 is most common, but other members of the Ig domain clan, Pfam:PF07679 and Pfam:PF07686 can be identified instead. The fourth Ig domain lacks the disulfide-bonded cysteines. [PRO:WCB]
PRO Category family
Parent PR:000000001 protein
Term Hierarchy Visualization DAG     OLS     Cytoscape


Functional Annotation
PRO Term GO Annotation Evidence
PR:000001810
CSF-1/PDGF receptor-type tyrosine-protein kinase
has_part Pfam:PF07686 Immunoglobulin V-set domain
has_part Pfam:PF07714 Protein tyrosine and serine/threonine kinase
has_part Pfam:PF07679 Immunoglobulin I-set domain
has_part Pfam:PF00047 Immunoglobulin domain

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