Protein Ontology Report - PDGFRB PR:000002035 - http://purl.obolibrary.org/obo/PR_000002035

Ontology Information
PRO ID	PR:000002035 Show OBO stanza / PAF
PRO name	beta-type platelet-derived growth factor receptor
Synonyms	PRO-short-label: EXACT: PDGFRB Gene-based: RELATED: PDGFR1 Other: EXACT: CD140 antigen-like family member B | CD140b | PDGF-R-beta | PDGFR-1 | PDGFR-beta | beta platelet-derived growth factor receptor | platelet-derived growth factor receptor 1 RELATED: Pdgfr
Definition	A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human PDGFRB gene or a 1:1 ortholog thereof. [PRO:WCB]
PRO Category	gene
Parent	PR:000001810 CSF-1/PDGF receptor-type tyrosine-protein kinase
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Independent Organism-Specific Category Number of Terms Category Number of Terms gene 1 organism-gene 3 sequence 2 organism-sequence 4 modification 4 organism-modification 5 union 0
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	IUPHARobj:1804, PIRSF:PIRSF500948

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All gene organism-gene sequence organism-sequence modification organism-modification
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:000049848 hPDGFRB/SigPep-/UnPhos:2 Tyr-857, PR:000026291 acts_upstream_of_or_within GO:0038083 peptidyl-tyrosine autophosphorylation PMID:9642269 PR:000049847 hPDGFRB/SigPep-/Phos:3 Tyr-857, MOD:00048|Ser-1104, MOD:00046 acts_upstream_of_or_within GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling decreased relative to PR:000049846 hPDGFRB/SigPep-/Phos:2 PMID:15271984 enables GO:0004713 protein tyrosine kinase activity decreased relative to PR:000049846 hPDGFRB/SigPep-/Phos:2 PMID:15271984 enables GO:0005515 protein binding decreased relative to PR:000049846 hPDGFRB/SigPep-/Phos:2 with PR:O14745 hSLC9A3R1 PMID:15271984 PR:000049846 hPDGFRB/SigPep-/Phos:2 Tyr-857, MOD:00048 acts_upstream_of_or_within GO:0018108 peptidyl-tyrosine phosphorylation increased relative to PR:000049848 hPDGFRB/SigPep-/UnPhos:2 PMID:1653029, PMID:9642269 enables GO:0004713 protein tyrosine kinase activity PMID:15994317, PMID:9642269 enables GO:0005515 protein binding increased relative to PR:000049848 hPDGFRB/SigPep-/UnPhos:2 with PR:P20936 hRASA1 PMID:1653029

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