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Protein Ontology Report - LCK

PR:000002998 - http://purl.obolibrary.org/obo/PR_000002998
Ontology Information
PRO ID PR:000002998 Show OBO stanza / PAF
PRO name tyrosine-protein kinase Lck
Synonyms
PRO-short-label: LCK
EXACT: LSK; T cell-specific protein-tyrosine kinase; leukocyte C-terminal Src kinase; lymphocyte cell-specific protein-tyrosine kinase; p56-LCK; proto-oncogene Lck; proto-oncogene tyrosine-protein kinase lck
Gene-based: Lsk-t
Definition A proto-oncogene SRC-like tyrosine-protein kinase that is a translation product of the human LCK gene or a 1:1 ortholog thereof. [PRO:CNA]
PRO Category gene
Parent PR:000002997 proto-oncogene SRC-like tyrosine-protein kinase
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 3
sequence 1 organism-sequence 4
modification 3 organism-modification 7
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

LCK forms found in complexes
LCK Component Complexes
PR:P06239 hLCK PR:000028449 CD4:Lck complex (human)

Functional Annotation
PRO Term GO Annotation Evidence
PR:000036619
hLCK/iso:1/Phos:1
Tyr-394/Tyr-505, MOD:00048
capable_of GO:0016301 kinase activity decreased relative to PR:000036622 hLCK/iso:1/Phos:2 PMID:9043947
PR:000036622
hLCK/iso:1/Phos:2
Tyr-394, MOD:00048
capable_of GO:0016301 kinase activity PMID:9043947
capable_of GO:0044877 protein-containing complex binding PMID:9043947

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