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Protein Ontology Report - RAF1

PR:000003244 - http://purl.obolibrary.org/obo/PR_000003244
Ontology Information
PRO ID PR:000003244 Show OBO stanza / PAF
PRO name RAF proto-oncogene serine/threonine-protein kinase
Synonyms
PRO-short-label: RAF1
EXACT: Raf-1; cRaf; proto-oncogene c-RAF
Gene-based: RAF
Definition A protein that is a translation product of the human RAF1 gene or a 1:1 ortholog thereof. [PRO:CNA]
PRO Category gene
Parent PR:000000001 protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 7
sequence 2 organism-sequence 6
modification 4 organism-modification 11
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000036643
hRAF1/iso:1/Phos:2
Ser-338/Ser-339, MOD:00046
capable_of GO:0005515 protein binding with PR:P10415 hBCL2 PMID:15849194
capable_of GO:0004674 protein serine/threonine kinase activity PMID:15849194
located_in GO:0005741 mitochondrial outer membrane PMID:15849194
participates_in GO:0043066 negative regulation of apoptotic process PMID:15849194
PR:P04049
hRAF1
capable_of GO:0005515 protein binding with PR:O60566 hBUB1B PMID:20703093
participates_in GO:0032877 positive regulation of DNA endoreduplication PMID:20703093
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0043066 negative regulation of apoptotic process PR:000036643 hRAF1/iso:1/Phos:2
Ser-338/Ser-339, MOD:00046
PMID:15849194
GO:0032877 positive regulation of DNA endoreduplication PR:P04049 hRAF1

PMID:20703093
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005741 mitochondrial outer membrane PR:000036643 hRAF1/iso:1/Phos:2
Ser-338/Ser-339, MOD:00046
PMID:15849194

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