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Protein Ontology Report - INPP5D

PR:000003302 - http://purl.obolibrary.org/obo/PR_000003302
Ontology Information
PRO ID PR:000003302 Show OBO stanza / PAF
PRO name phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1
Synonyms
PRO-short-label: INPP5D
EXACT: SH2 domain-containing inositol 5'-phosphatase 1; SH2 domain-containing inositol phosphatase 1; SH2 domain-containing inositol-5'-phosphatase 1; SHIP-1; SIP-145; hp51CN; inositol polyphosphate-5-phosphatase D; inositol polyphosphate-5-phosphatase of 145 kDa; p150Ship
Gene-based: 7a33; SHIP; SHIP1
Definition A protein that is a translation product of the human INPP5D gene or a 1:1 ortholog thereof. [PRO:HJD]
PRO Category gene
Parent PR:000000001 protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 3
sequence 6 organism-sequence 9
modification 4 organism-modification 1
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:Q9ES52-2
mINPP5D/iso:2
capable_of GO:0017124 SH3 domain binding MGI:85578, PMID:8643691
capable_of GO:0004445 inositol-polyphosphate 5-phosphatase activity MGI:85578, PMID:8643691
capable_of GO:0051425 PTB domain binding MGI:85577, PMID:8654924
capable_of GO:0034594 phosphatidylinositol trisphosphate phosphatase activity MGI:85574, PMID:8890215
participates_in GO:0008285 negative regulation of cell proliferation MGI:85574, PMID:8890215
PR:000036644
mINPP5D/iso:2/Phos:1
capable_of GO:0005515 protein binding with PR:P98083 mSHC1 PMID:8643691
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0008285 negative regulation of cell proliferation PR:Q9ES52-2 mINPP5D/iso:2

MGI:85574, PMID:8890215

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