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Protein Ontology Report - KDM1B

PR:000003320 - http://purl.obolibrary.org/obo/PR_000003320
Ontology Information
PRO ID PR:000003320 Show OBO stanza / PAF
PRO name lysine-specific histone demethylase 1B
Synonyms
PRO-short-label: KDM1B
EXACT: flavin-containing amine oxidase domain-containing protein 1; lysine-specific histone demethylase 2
Gene-based: AOF1; C6orf193; LSD2
Definition A protein that is a translation product of the human KDM1B gene or a 1:1 ortholog thereof. [MGI:2145261, PRO:HJD]
PRO Category gene
Parent PR:000000001 protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 5
sequence 1 organism-sequence 6
modification 0 organism-modification 0
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:Q8CIG3
mKDM1B
participates_in GO:0006349 regulation of gene expression by genetic imprinting PMID:19727073
participates_in GO:0043046 DNA methylation involved in gamete generation PMID:19727073
PR:Q8CIG3-1
mKDM1B/iso:1
capable_of GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific) PMID:19727073
capable_of GO:0008270 zinc ion binding PMID:19407342
capable_of GO:0034649 histone demethylase activity (H3-monomethyl-K4 specific) PMID:19407342
capable_of GO:0050660 flavin adenine dinucleotide binding PMID:19407342
capable_of GO:0034720 histone H3-K4 demethylation PMID:19407342
capable_of GO:0034649 histone demethylase activity (H3-monomethyl-K4 specific) PMID:19727073
capable_of GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific) PMID:19407342
located_in GO:0005634 nucleus PMID:19727073
participates_in GO:0034720 histone H3-K4 demethylation PMID:19727073
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0006349 regulation of gene expression by genetic imprinting PR:Q8CIG3 mKDM1B

PMID:19727073
GO:0043046 DNA methylation involved in gamete generation PR:Q8CIG3 mKDM1B

PMID:19727073
GO:0034720 histone H3-K4 demethylation PR:Q8CIG3-1 mKDM1B/iso:1

PMID:19727073
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:Q8CIG3-1 mKDM1B/iso:1

PMID:19727073

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