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Protein Ontology Report - BUB3

PR:000004856 - http://purl.obolibrary.org/obo/PR_000004856
Ontology Information
PRO ID PR:000004856 Show OBO stanza / PAF
PRO name mitotic checkpoint protein BUB3
Synonyms
PRO-short-label: BUB3
EXACT: WD repeat type I transmembrane protein A72.5
Definition A protein that is a translation product of the human BUB3 gene or a 1:1 ortholog thereof. [PRO:DNx]
PRO Category gene
Parent PR:000000001 protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 7
sequence 1 organism-sequence 5
modification 2 organism-modification 4
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

BUB3 forms found in complexes
BUB3 Component Complexes
PR:O42860 Spom972h-BUB3 PR:000035569 BUB1:BUB3 complex (Schizosaccharomyces pombe 972h-)
PR:O43684 hBUB3 PR:000035576 BUB1:BUB3:APC complex (human)
PR:O43684 hBUB3 PR:000035567 BUB1:BUB3:MAD1L1 complex (human)
PR:O43684 hBUB3 PR:000035511 BUB1B:BUB3:MAD2:CDC20 complex (human)
PR:O43684 hBUB3 PR:000035564 BUB1:BUB3 complex (human)
PR:O43684 hBUB3 PR:000035563 BUB1B:BUB3 complex (human)
PR:P26449 yBUB3 PR:000035565 BUB1:BUB3 complex (yeast)
PR:Q9YGY3 frog-BUB3 PR:000035512 BUB1B:BUB3:MAD2:CDC20 complex (frog)

Functional Annotation
PRO Term GO Annotation Evidence
PR:P26449
yBUB3
capable_of GO:0005515 protein binding with PR:000035536 ySPC105/Phos:1 PMID:22521787
located_in GO:0000776 kinetochore PMID:22521787
participates_in GO:0006974 cellular response to DNA damage stimulus PMID:15514023
PR:000035437
hBUB3/Phos:1
Ser-18, MOD:00046
participates_in GO:0012501 programmed cell death increased relative to PR:000035454 hBUB3/PhosRes- PMID:20057499
PR:O43684
hBUB3
capable_of GO:0005515 protein binding with PR:Q12834 hCDC20 BioGRID:BG-561804, MINT:MINT-8183848
capable_of GO:0005515 protein binding with PR:O60566 hBUB1B PMID:17785528
capable_of GO:0005515 protein binding with PR:O15350-1 hTP73/iso:1 PMID:20057499
capable_of GO:0005515 protein binding with PR:O43683 hBUB1 PMID:10198256
capable_of GO:0005515 protein binding with PR:Q9Y6D9 hMAD1L1 PMID:10198256
capable_of GO:0005515 protein binding with PR:O15350-3 hTP73/iso:3 PMID:20057499
capable_of GO:0005515 protein binding with PR:P25054 hAPC BioGRID:BG-302961
capable_of GO:0005515 protein binding with PR:O15350-2 hTP73/iso:2 PMID:20057499
capable_of GO:0005515 protein binding with PR:Q13257 hMAD2L1 BioGRID:BG-718926
capable_of GO:0005515 protein binding with PR:O15350-5 hTP73/iso:5 PMID:20057499
located_in GO:0000776 kinetochore PMID:11283619
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0012501 programmed cell death PR:000035437 hBUB3/Phos:1
Ser-18, MOD:00046
increased relative to PR:000035454 hBUB3/PhosRes-
PMID:20057499
GO:0006974 cellular response to DNA damage stimulus PR:P26449 yBUB3

PMID:15514023
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0000776 kinetochore PR:O43684 hBUB3

PMID:11283619
PR:P26449 yBUB3

PMID:22521787

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