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Protein Ontology Report - CAPZB

PR:000005032 - http://purl.obolibrary.org/obo/PR_000005032
Ontology Information
PRO ID PR:000005032 Show OBO stanza / PAF
PRO name F-actin-capping protein subunit beta
Synonyms
PRO-short-label: EXACT: CAPZB
Gene-based: RELATED: Cappb1
Other: EXACT: CapZ beta
Definition A protein that is a translation product of the human CAPZB gene or a 1:1 ortholog thereof. [PRO:DNx]
PRO Category gene
Parent PR:000000001 protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 10
sequence 3 organism-sequence 8
modification 1 organism-modification 1
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

CAPZB forms found in complexes
CAPZB Component Complexes
PR:P47757-2 mCAPZB/iso:2 PR:000035900 F-actin capping protein complex alpha-1 beta-2 (mouse)
PR:P47757-2 mCAPZB/iso:2 PR:000035901 F-actin capping protein complex alpha-2 beta-2 (mouse)

Functional Annotation
PRO Term GO Annotation Evidence
PR:P47757-4
mCAPZB/iso:Capzb3
located_in GO:0001669 acrosomal vesicle MGI:3848085, PMID:19341723
PR:P47757-2
mCAPZB/iso:2
acts_upstream_of_or_within GO:0031175 neuron projection development MGI:4397629, PMID:19806181
acts_upstream_of_or_within GO:0051016 barbed-end actin filament capping MGI:3758397, PMID:17656356
acts_upstream_of_or_within GO:0055001 muscle cell development MGI:1350695, PMID:10601341
acts_upstream_of_or_within GO:0030032 lamellipodium assembly MGI:4397629, PMID:19806181
acts_upstream_of_or_within GO:0031115 negative regulation of microtubule polymerization MGI:4397629, PMID:19806181
enables GO:0051015 actin filament binding MGI:3758397, PMID:17656356
enables GO:0048487 beta-tubulin binding with PR:Q9ERD7 mTUBB3 MGI:4397629, PMID:19806181
enables GO:0005515 protein binding with PR:Q91YR1 mTWF1 MGI:3773286, PMID:11604420
located_in GO:0014704 intercalated disc MGI:1350695, PMID:10601341
located_in GO:0014704 intercalated disc MGI:68935, PMID:7929588
part_of GO:0008290 F-actin capping protein complex with PR:P47754 mCAPZA2 MGI:4397629, PMID:19806181
part_of GO:0008290 F-actin capping protein complex MGI:3773286, PMID:11604420
PR:P47757-1
mCAPZB/iso:1
acts_upstream_of_or_within GO:0090036 regulation of protein kinase C signaling MGI:3777904, PMID:12089068
acts_upstream_of_or_within GO:0055001 muscle cell development MGI:1350695, PMID:10601341
located_in GO:0030018 Z disc MGI:1350695, PMID:10601341
located_in GO:0030018 Z disc MGI:68935, PMID:7929588
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0014704 intercalated disc PR:P47757-2 mCAPZB/iso:2

MGI:1350695, PMID:10601341
PR:P47757-2 mCAPZB/iso:2

MGI:68935, PMID:7929588
GO:0030018 Z disc PR:P47757-1 mCAPZB/iso:1

MGI:1350695, PMID:10601341
PR:P47757-1 mCAPZB/iso:1

MGI:68935, PMID:7929588
GO:0001669 acrosomal vesicle PR:P47757-4 mCAPZB/iso:Capzb3

MGI:3848085, PMID:19341723

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