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Protein Ontology Report - DEGS2

PR:000006414 - http://purl.obolibrary.org/obo/PR_000006414
Ontology Information
PRO ID PR:000006414 Show OBO stanza / PAF
PRO name sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2
Synonyms
PRO-short-label: DEGS2
EXACT: degenerative spermatocyte homolog 2; sphingolipid 4-desaturase; sphingolipid C4-monooxygenase; sphingolipid Delta(4)-desaturase/C4-hydroxylase DES2
Gene-based: C14orf66
Definition A protein that is a translation product of the human DEGS2 gene or a 1:1 ortholog thereof. [PRO:DNx]
PRO Category gene
Parent PR:000000001 protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 3
sequence 2 organism-sequence 3
modification 0 organism-modification 0
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000022016
DEGS2/iso:1
capable_of GO:0000170 sphingosine hydroxylase activity MGI:3694278, PMID:16571104
capable_of GO:0000170 sphingosine hydroxylase activity MGI:3056825, PMID:15474011
participates_in GO:0046513 ceramide biosynthetic process MGI:3694278, PMID:16571104
participates_in GO:0006667 sphinganine metabolic process MGI:3694278, PMID:16571104
PR:Q8R2F2
mDEGS2
capable_of GO:0042284 sphingolipid delta-4 desaturase activity PMID:11937514
participates_in GO:0030148 sphingolipid biosynthetic process PMID:11937514
participates_in GO:0006667 sphinganine metabolic process PMID:11937514
PR:Q8R2F2-1
mDEGS2/iso:1
capable_of GO:0000170 sphingosine hydroxylase activity PMID:15474011, PMID:16571104
capable_of GO:0000170 sphingosine hydroxylase activity PMID:16571104
participates_in GO:0046513 ceramide biosynthetic process PMID:16571104
participates_in GO:0006667 sphinganine metabolic process PMID:16571104
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0030148 sphingolipid biosynthetic process PR:Q8R2F2 mDEGS2

PMID:11937514
GO:0006667 sphinganine metabolic process PR:000022016 DEGS2/iso:1

MGI:3694278, PMID:16571104
PR:Q8R2F2 mDEGS2

PMID:11937514
PR:Q8R2F2-1 mDEGS2/iso:1

PMID:16571104
GO:0046513 ceramide biosynthetic process PR:000022016 DEGS2/iso:1

MGI:3694278, PMID:16571104
PR:Q8R2F2-1 mDEGS2/iso:1

PMID:16571104

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