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Protein Ontology Report - SIAH1

PR:000014860 - http://purl.obolibrary.org/obo/PR_000014860
Ontology Information
PRO ID PR:000014860 Show OBO stanza / PAF
PRO name E3 ubiquitin-protein ligase SIAH1
Alternate ID PR:000015946
Synonyms
PRO-short-label: SIAH1
EXACT: Siah-1; Siah-1a; seven in absentia homolog 1; seven in absentia homolog 1a
RELATED: HUMSIAH
Definition A protein that is a translation product of the human SIAH1 gene or a 1:1 ortholog thereof. [PRO:DNx]
PRO Category gene
Parent PR:000000001 protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 5
sequence 1 organism-sequence 5
modification 1 organism-modification 2
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000025641
hSIAH1/iso:1/Phos:1
Tyr-100/Tyr-126, MOD:00048
capable_of GO:0005515 protein binding increased relative to PR:000045369 hSIAH1/iso:1/UnPhos:1 with PR:Q69ZI1-1 mSH3RF1/iso:1 PMID:16230351
participates_in GO:0043525 positive regulation of neuron apoptotic process PMID:16230351
participates_in GO:0070304 positive regulation of stress-activated protein kinase signaling cascade PMID:16230351
PR:000045369
hSIAH1/iso:1/UnPhos:1
Tyr-100/Tyr-126, PR:000026291
capable_of GO:0005515 protein binding with PR:Q69ZI1 mSH3RF1 PMID:16230351
participates_in GO:0070304 positive regulation of stress-activated protein kinase signaling cascade PMID:16230351
participates_in GO:0043525 positive regulation of neuron apoptotic process PMID:16230351
PR:Q920M9-1
rSIAH1/iso:1
capable_of GO:0005515 protein binding with PR:Q71F54 rSH3RF1 PMID:16230351
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0070304 positive regulation of stress-activated protein kinase signaling cascade PR:000025641 hSIAH1/iso:1/Phos:1
Tyr-100/Tyr-126, MOD:00048
PMID:16230351
PR:000045369 hSIAH1/iso:1/UnPhos:1
Tyr-100/Tyr-126, PR:000026291
PMID:16230351
GO:0043525 positive regulation of neuron apoptotic process PR:000025641 hSIAH1/iso:1/Phos:1
Tyr-100/Tyr-126, MOD:00048
PMID:16230351
PR:000045369 hSIAH1/iso:1/UnPhos:1
Tyr-100/Tyr-126, PR:000026291
PMID:16230351

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