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Protein Ontology Report - YAP1

PR:000017522 -
Ontology Information
PRO ID PR:000017522 Show OBO stanza / PAF
PRO name transcriptional coactivator YAP1
PRO-short-label: YAP1
EXACT: 65 kDa Yes-associated protein; YAP65; Yes-associated protein 1; Yes-associated protein YAP65 homolog; protein yorkie homolog; yorkie homolog
Gene-based: Yap
Definition A protein that is a translation product of the human YAP1 gene or a 1:1 ortholog thereof. [PRO:DNx]
PRO Category gene
Parent PR:000000001 protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 4
sequence 0 organism-sequence 15
modification 0 organism-modification 6
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
Tyr-357, PR:000026291
capable_of GO:0005515 protein binding with PR:O15350 hTP73 PMID:21214929, PMID:21562856
Ser-127, MOD:00046
associated_with_disease_progression DOID:162 cancer PMID:21214929
associated_with_disease_suppression DOID:10652 Alzheimer's disease PMID:21945154
capable_of GO:0005515 protein binding decreased relative to PR:000037509 hYAP1/UnPhos:1 with PR:O15350 hTP73 PMID:21945154
capable_of GO:0005515 protein binding with PR:000003237 14-3-3 protein PMID:21214929
Tyr-357, MOD:00048
associated_with_disease_progression DOID:10652 Alzheimer's disease PMID:21562856
associated_with_disease_suppression DOID:162 cancer PMID:21214929
capable_of GO:0005515 protein binding increased relative to PR:000037507 hYAP1/iso:3/UnPhos:1 with PR:O15350 hTP73 PMID:21214929, PMID:21562856
located_in GO:0005634 nucleus PMID:21562856
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:000037508 hYAP1/iso:3/Phos:1
Tyr-357, MOD:00048