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Protein Ontology Report - LPS:mCD14

PR:000025493 - http://purl.obolibrary.org/obo/PR_000025493
Ontology Information
PRO ID PR:000025493 Show OBO stanza / PAF
PRO name LPS:GPI-anchored CD14 complex
Synonyms
PRO-short-label: LPS:mCD14
EXACT: mCD14/LPS complex
Definition An LPS:CD14 complex that contains the membrane bound form of CD14 bound to lipopolysaccharides (LPS). [PMID:7539760]
PRO Category complex
Parent PR:000037465 LPS:CD14 complex
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
complex 1 organism-complex 2
Term Hierarchy Visualization DAG     OLS     Cytoscape

Complex Forms
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits
Complex PRO ID Name Short Label Definition Number in Complex
PR:000037464 PR:000035702 CD14 molecule isoform 1 cleaved 2 GPI-anchored form (human) hCD14/iso:1/Clv:2/anchored A CD14 molecule isoform 1 cleaved 2 GPI-anchored form in human. UniProtKB:P08571-1, 20-345, Asn-345, MOD:00167. [Reactome:R-HSA-166033, Reactome:R-HSA-2201284]
CHEBI:16412 lipopolysaccharide lipopolysaccharide Natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria). [fake:1]
PR:000025493 PR:000002149 CD14 molecule isoform 1 cleaved 2 GPI-anchored form CD14/iso:1/Clv:2/anchored A CD14 molecule isoform 1 cleaved 2 that is the mature membrane-bound form of this protein. Example: UniProtKB:P08571-1, 20-345, Asn-345, MOD:00167. [PMID:3385210, PRO:CNA]
CHEBI:16412 lipopolysaccharide lipopolysaccharide Natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria). [fake:1]
PR:000037468 PR:000037470 CD14 molecule isoform 1 cleaved 2 GPI-anchored form (mouse) mCD14/iso:1/Clv:2/anchored A CD14 molecule isoform 1 cleaved 2 GPI-anchored form in mouse. UniProtKB:P10810-1, 16-336, Asn-336, MOD:00167. [PMID:10601848, PMID:18606699, PRO:CNA]
CHEBI:16412 lipopolysaccharide lipopolysaccharide Natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria). [fake:1]


Functional Annotation
PRO Term GO Annotation Evidence
PR:000037464
LPS:GPI-anchored CD14 complex (human)
located_in GO:0005886 plasma membrane Reactome:REACT_7856
participates_in GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0034142 toll-like receptor 4 signaling pathway PR:000037464 LPS:GPI-anchored CD14 complex (human)

Reactome:REACT_6894
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005886 plasma membrane PR:000037464 LPS:GPI-anchored CD14 complex (human)

Reactome:REACT_7856

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