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Protein Ontology Report - LPS:sCD14alpha

PR:000025494 - http://purl.obolibrary.org/obo/PR_000025494
Ontology Information
PRO ID PR:000025494 Show OBO stanza / PAF
PRO name LPS:secreted CD14 alpha
Synonyms
PRO-short-label: LPS:sCD14alpha
EXACT: CD14sLPS complex; sCD14/LPS complex
Definition An LPS:secreted CD14 complex that contains the low M(r) soluble form of CD14 bound to lipopolysaccharides (LPS). [PMID:16861002, PMID:7681988, PRO:CNA, PRO:DAN]
PRO Category complex
Parent PR:000029989 LPS:secreted CD14 complex
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
complex 1 organism-complex 1
Term Hierarchy Visualization DAG     OLS     Cytoscape

Complex Forms
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits
Complex PRO ID Name Short Label Definition Number in Complex
PR:000025494 CHEBI:16412 lipopolysaccharide lipopolysaccharide Natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria). [fake:1]
PR:000037463 PR:000035703 CD14 molecule isoform 1 cleaved 2 soluble form (human) hCD14/iso:1/Clv:2/soluble A CD14 molecule isoform 1 cleaved 2 soluble form in human. UniProtKB:P08571-1, 20-345. [PRO:DNx, UniProtKB:P08571]
CHEBI:16412 lipopolysaccharide lipopolysaccharide Natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria). [fake:1]


Functional Annotation
PRO Term GO Annotation Evidence
PR:000037463
LPS:secreted CD14 alpha (human)
located_in GO:0005615 extracellular space Reactome:REACT_7856
participates_in GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0034142 toll-like receptor 4 signaling pathway PR:000037463 LPS:secreted CD14 alpha (human)

Reactome:REACT_6894
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005615 extracellular space PR:000037463 LPS:secreted CD14 alpha (human)

Reactome:REACT_7856

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