PRO Entry Report - PR:000025974

Protein Ontology Report - TGF-beta 1:type II receptor:Phospho-type I receptor:SARA:SMAD2 complex

PR:000025974 - http://purl.obolibrary.org/obo/PR_000025974

Complex Forms Complex Subunits

Ontology Information

PRO ID

PR:000025974 Show OBO stanza

PRO name

TGF-beta 1:type II receptor:Phospho-type I receptor:SARA:SMAD2 complex

Definition

A transforming growth factor beta receptor complex that is composed of the two receptor subunits, TGF-beta 1 bound, sara and smad2. [PRO:CNA]

PRO Category

complex

Parent

GO:0032991 protein-containing complex

Terms by PRO Category

Retrieve All terms OBO Stanza / PAF

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
complex	1	organism-complex	1

Term Hierarchy Visualization

DAG

OLS

Cytoscape

Complex Forms

PRO ID & Category Annotation Subunits	Name	Short Label	Definition & Comment

Complex Subunits

Complex	PRO ID	Name	Short Label	Definition
PR:000025974	PR:000000125	zinc finger FYVE domain-containing protein 9	ZFYVE9	A sara-type zinc finger FYVE domain-containing protein that is a translation product of the human ZFYVE9 gene or a 1:1 ortholog thereof. [PRO:CNA]
	PR:000025976	transforming growth factor beta type II receptor homodimeric complex phosphorylated form	(TGFBR2/iso:1/SigPep-/Phos:1)*2	A protein-containing complex that is composed of two TGF-beta receptor type-2 isoform RII-1, signal peptide removed forms that have been phosphorylated upon TGF-beta binding. [PRO:CNA]
	PR:000025975	transforming growth factor beta type I receptor homodimeric complex phosphorylated form	(TGFBR1/iso:1/SigPep-/Phos:1)*2	A protein-containing complex that is composed of two TGF-beta receptor type-1 isoform 1, signal peptide removed forms that have been phosphorylated by activated TGF-beta type II receptor. [PRO:CNA]
	PR:000025973	smad2 isoform unmodified form	SMAD2/iso:[Long/Short]/UnMod	A smad2 unmodified form that corresponds to either isoform Long or isoform Short. [PMID:19135894, PRO:CNA, PRO:DAN]
	PR:000025925	dimeric TGF-beta 1	(TGFB1)*2	A protein-containing complex that is homodimer of TGF-beta 1. [PRO:CNA]
PR:000025965	PR:O95405	zinc finger FYVE domain-containing protein 9 (human)	hZFYVE9	A zinc finger FYVE domain-containing protein 9 that is encoded in the genome of human. [PRO:CNA]
	PR:000025963	transforming growth factor beta type II receptor homodimeric complex phosphorylated form (human)	h(TGFBR2/iso:1/SigPep-/Phos:1)*2	A transforming growth factor beta type II receptor homodimeric complex phosphorylated form whose components are encoded in the genome of human. [PRO:CNA]
	PR:000025961	transforming growth factor beta type I receptor homodimeric complex phosphorylated form (human)	h(TGFBR1/iso:1/SigPep-/Phos:1)*2	A transforming growth factor beta type I receptor homodimeric complex phosphorylated form in human. [PRO:CNA]
	PR:000045371	smad2 isoform Long unphosphorylated 1 (human)	hSMAD2/iso:Long/UnPhos:1	A mothers against decapentaplegic homolog 2 isoform Long (human) that lacks phosphorylation on the two last Ser of the C-terminal SSxS motif in human. UniProtKB:Q15796-1, Ser-465/Ser-467, PR:000026291. [PRO:CNA]
	PR:000025926	dimeric TGF-beta 1 (human)	h(TGFB1)*2	A dimeric TGF-beta 1 whose components are encoded in the genome of human. [PRO:CNA, Reactome:R-HSA-170852]

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