| Complex |
PRO ID |
Name |
Short Label |
Definition |
Number in Complex |
| PR:000027182 |
PR:000001740 |
myeloid differentiation primary response protein MyD88 |
MYD88 |
A protein that is a translation product of the human MYD88 gene or a 1:1 ortholog thereof. This protein is an adapter involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
[PMID:9575168, PRO:CNA]
|
2 |
| PR:000003296 |
lymphocyte antigen 96 |
LY96 |
A protein that is a translation product of the human LY96 gene or a 1:1 ortholog thereof.
[TLR:AMM]
|
2 |
| PR:000001780 |
interleukin-1 receptor-associated kinase 4 |
IRAK4 |
A protein that is a translation product of the human IRAK4 gene or a 1:1 ortholog thereof. The archetypical form consists of an N-terminal Death domain (Pfam:PF00531) and a C-terminal Protein kinase domain (Pfam:PF00069). This protein is an essential component of innate immunity.
[PMID:11960013, PMID:16177054, PRO:CNA]
|
|
| PR:000001751 |
Toll/interleukin-1 receptor domain-containing adapter protein |
TIRAP |
A protein that is a translation product of the human TIRAP gene or a 1:1 ortholog thereof.
[PRO:CNA]
|
2 |
| PR:000001155 |
Toll-like receptor 4 |
TLR4 |
A Toll-like receptor that is a translation product of the human TLR4 gene or a 1:1 ortholog thereof.
[PRO:CNA]
|
2 |
| CHEBI:16412 |
lipopolysaccharide |
lipopolysaccharide |
Natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
[fake:1]
|
2 |
| PR:000027183 |
PR:Q99836-1 |
myeloid differentiation primary response protein MyD88 isoform 1 (human) |
hMYD88/iso:1 |
A myeloid differentiation primary response protein MyD88 isoform 1 that is encoded in the genome of human.
[PRO:CNA]
|
|
| PR:P58753-1 |
Toll/interleukin-1 receptor domain-containing adapter protein isoform 1 (human) |
hTIRAP/iso:1 |
A Toll/interleukin-1 receptor domain-containing adapter protein isoform 1 that is encoded in the genome of human.
[PRO:CNA]
|
|
| PR:000025786 |
lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (human) |
hLY96/iso:1/SigPep-/NGlyco:1 |
A lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 in human. UniProtKB:Q9Y6Y9-1, 19-160, Asn-26/Asn-114, MOD:00160.
[PMID:11593030, PMID:11706042, PMID:17569869, TLR:AMM]
|
|
| PR:000027184 |
interleukin-1 receptor-associated kinase 4 unmodified form (human) |
hIRAK4/UnMod |
An interleukin-1 receptor-associated kinase 4 unmodified form in human.
[PRO:CNA]
|
|
| PR:000025787 |
Toll-like receptor 4 isoform 1, signal peptide removed N-glycosylated 1 (human) |
hTLR4/iso:1/SigPep-/NGlyco:1 |
A Toll-like receptor 4 isoform 1, signal peptide removed N-glycosylated 1 in human. UniProtKB:O00206-1, 24-839, Asn-35/Asn-173/Asn-205/Asn-282/Asn-309/Asn-497/Asn-526/Asn-575/Asn-624, MOD:00160.
[PMID:11706042, PMID:19252480]
|
|
| CHEBI:16412 |
lipopolysaccharide |
lipopolysaccharide |
Natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
[fake:1]
|
|
| PR:000027187 |
PR:P22366-1 |
myeloid differentiation primary response protein MyD88 isoform 1 (mouse) |
mMYD88/iso:1 |
A myeloid differentiation primary response protein MyD88 isoform 1 that is encoded in the genome of mouse.
[PMID:11909531, PRO:CNA]
|
|
| PR:Q99JY1 |
Toll/interleukin-1 receptor domain-containing adapter protein (mouse) |
mTIRAP |
A Toll/interleukin-1 receptor domain-containing adapter protein that is encoded in the genome of mouse.
[OMA:Q99JY1, PRO:CNA]
|
|
| PR:000027171 |
lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (mouse) |
mLY96/iso:1/SigPep-/NGlyco:1 |
A lymphocyte antigen 96 isoform 1, signal peptide removed glycosylated form in mouse that has been N-glycosylated on Asn residues at positions 26, 114, and 150 of the amino acid sequence represented by UniProtKB:Q9JHF9-1. UniProtKB:Q9JHF9-1, 19-160, Asn-26/Asn-114/Asn-150, MOD:00160.
[PMID:17803912, PRO:CNA]
|
|
| PR:000027181 |
interleukin-1 receptor-associated kinase 4 unmodified form (mouse) |
mIRAK4/UnMod |
An interleukin-1 receptor-associated kinase 4 unmodified form in mouse.
[PRO:CNA]
|
|
| PR:000027172 |
Toll-like receptor 4 isoform 1, signal peptide removed N-glycosylated 1 (mouse) |
mTLR4/iso:1/SigPep-/NGlyco:1 |
A Toll-like receptor 4 isoform 1, signal peptide removed form in mouse that has been N-glycosylated on Asn residues at positions 34, 75, 172, 204, 237, 307, 492, 524 and 572 of the amino acid sequence represented by UniProtKB:Q9QUK6-1. UniProtKB:Q9QUK6-1, 26-835, Asn-34/Asn-75/Asn-172/Asn-204/Asn-237/Asn-307/Asn-492/Asn-524/Asn-572, MOD:00160.
[PMID:17803912, PRO:CNA]
|
|
| CHEBI:16412 |
lipopolysaccharide |
lipopolysaccharide |
Natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
[fake:1]
|
|
| PR:000027192 |
PR:Q99836-1 |
myeloid differentiation primary response protein MyD88 isoform 1 (human) |
hMYD88/iso:1 |
A myeloid differentiation primary response protein MyD88 isoform 1 that is encoded in the genome of human.
[PRO:CNA]
|
|
| PR:P58753-1 |
Toll/interleukin-1 receptor domain-containing adapter protein isoform 1 (human) |
hTIRAP/iso:1 |
A Toll/interleukin-1 receptor domain-containing adapter protein isoform 1 that is encoded in the genome of human.
[PRO:CNA]
|
|
| PR:000025786 |
lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (human) |
hLY96/iso:1/SigPep-/NGlyco:1 |
A lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 in human. UniProtKB:Q9Y6Y9-1, 19-160, Asn-26/Asn-114, MOD:00160.
[PMID:11593030, PMID:11706042, PMID:17569869, TLR:AMM]
|
|
| PR:000027191 |
interleukin-1 receptor-associated kinase 4 isoform 1 phosphorylated 1 (human) |
hIRAK4/iso:1/Phos:1 |
An interleukin-1 receptor-associated kinase 4 isoform 1 phosphorylated 1 in human. UniProtKB:Q9NWZ3-1, Thr-342/Thr-345, MOD:00047|Ser-346, MOD:00046.
[PMID:17141195, PRO:CNA]
|
|
| PR:000025787 |
Toll-like receptor 4 isoform 1, signal peptide removed N-glycosylated 1 (human) |
hTLR4/iso:1/SigPep-/NGlyco:1 |
A Toll-like receptor 4 isoform 1, signal peptide removed N-glycosylated 1 in human. UniProtKB:O00206-1, 24-839, Asn-35/Asn-173/Asn-205/Asn-282/Asn-309/Asn-497/Asn-526/Asn-575/Asn-624, MOD:00160.
[PMID:11706042, PMID:19252480]
|
|
| CHEBI:16412 |
lipopolysaccharide |
lipopolysaccharide |
Natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
[fake:1]
|
|
|
DAG
OLS
Cytoscape