| PRO ID |
PR:000027775
Show OBO stanza
|
| PRO name |
estrogen receptor isoform 1 phosphorylated 4 |
| Synonyms |
| PRO-short-label: |
EXACT: |
ESR1/iso:1/Phos:4 |
|
| Definition |
An estrogen receptor isoform 1 that has been phosphorylated on a Thr located in the helix 1 of the hormone binding domain. This highly conserved Thr residue is part of a leucine -rich nuclear export signal sequence and phosphorylation at this site blocks ERalpha nuclear export and promotes its transcriptional activation. Example: UniProtKB:P03372-1, Thr-311, MOD:00047.
[PMID:12138194, PRO:PD]
|
| PRO Category |
modification |
| Parent |
PR:000027721 estrogen receptor isoform 1 |
| Term Hierarchy Visualization |
 DAG
 OLS
Cytoscape
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