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Protein Ontology Report - hTP53/iso:1/Me:3

PR:000027808 - http://purl.obolibrary.org/obo/PR_000027808
Ontology Information
PRO ID PR:000027808 Show OBO stanza / PAF
PRO name cellular tumor antigen p53 isoform 1 methylated 3 (human)
Synonyms
PRO-short-label: hTP53/iso:1/Me:3
EXACT: p53-mLys372
PRO-proteoform-std: UniProtKB:P04637-1, Lys-372, MOD:00663
Definition A cellular tumor antigen p53 isoform 1 methylated 3 in human. This modification promotes p53 stability and inhibits Smyd2 mediated p53 methylation at Lys-370. UniProtKB:P04637-1, Lys-372, MOD:00663. [PMID:15525938, PRO:PD]
Comment Methylase=("SETD7"; PR:Q8WTS6; Lys-372).
PRO Category organism-modification
Parent PR:000027807 cellular tumor antigen p53 isoform 1 methylated 3
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000027808
hTP53/iso:1/Me:3
Lys-372, MOD:00663
located_in GO:0005634 nucleus PMID:15525938
participates_in GO:0045893 positive regulation of transcription, DNA-templated PMID:15525938
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0045893 positive regulation of transcription, DNA-templated PR:000027808 hTP53/iso:1/Me:3
Lys-372, MOD:00663
PMID:15525938
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:000027808 hTP53/iso:1/Me:3
Lys-372, MOD:00663
PMID:15525938

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