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Protein Ontology Report - hBUB1/Phos:7

PR:000035412 - http://purl.obolibrary.org/obo/PR_000035412
Ontology Information
PRO ID PR:000035412 Show OBO stanza / PAF
PRO name mitotic checkpoint serine/threonine-protein kinase BUB1 CDK-consensus sites phosphorylated 7 (human)
Synonyms
PRO-short-label: hBUB1/Phos:7
PRO-proteoform-std: UniProtKB:O43683-1, Ser-593, MOD:00046|Thr-609, MOD:00047
Definition A BUB1 CDK-consensus sites phosphorylated form in human. Phosphorylation occurs during mitosis and spindle disruption (e.g. with nocodazole). Thr-609 phosphorylation is critical for interaction with PLK1. Example: UniProtKB:O43683-1, Ser-593, MOD:00046|Thr-609, MOD:00047. [PMID:16760428, PRO:KER]
Comment Kinase=("CDK1"; PR:000003271).
PRO Category organism-modification
Parent PR:000035413 BUB1 CDK-consensus sites phosphorylated form
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000035412
hBUB1/Phos:7
Ser-593, MOD:00046|Thr-609, MOD:00047
capable_of GO:0005515 protein binding increased relative to PR:000035414 Spom972h-BUB1/PhosRes- with PR:Q9NQS7 hINCENP PMID:16760428
participates_in GO:0034501 protein localization to kinetochore PMID:16760428
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0034501 protein localization to kinetochore PR:000035412 hBUB1/Phos:7
Ser-593, MOD:00046|Thr-609, MOD:00047
PMID:16760428

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