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Protein Ontology Report - phosphoBUB1:PLK1 complex (human)

PR:000035581 - http://purl.obolibrary.org/obo/PR_000035581
Ontology Information
PRO ID PR:000035581 Show OBO stanza
PRO name phosphoBUB1:PLK1 complex (human)
Synonyms
EXACT: hpBUB1:hPLK1 complex
Definition A BUB1:PLK1 complex that contains a phosphorylated form of BUB1, and whose components are encoded in the genome of human. [PMID:16760428, PRO:KER]
PRO Category organism-complex
Parent PR:000035580 BUB1:PLK1 complex
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-complex 1
Term Hierarchy Visualization DAG     OLS     Cytoscape

Complex Forms
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits
Complex PRO ID Name Short Label Definition Number in Complex
PR:000035581 PR:P53350 serine/threonine-protein kinase PLK1 (human) hPLK1 A serine/threonine-protein kinase PLK1 that is encoded in the genome of human. [PMID:16129782, PMID:16580887, PMID:16760428, PMID:17376779, PMID:20624902, PMID:20823832, PRO:KER]
PR:000035412 mitotic checkpoint serine/threonine-protein kinase BUB1 CDK-consensus sites phosphorylated 7 (human) hBUB1/Phos:7 A BUB1 CDK-consensus sites phosphorylated form in human. Phosphorylation occurs during mitosis and spindle disruption (e.g. with nocodazole). Thr-609 phosphorylation is critical for interaction with PLK1. Example: UniProtKB:O43683-1, Ser-593, MOD:00046|Thr-609, MOD:00047. [PMID:16760428, PRO:KER]


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