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Protein Ontology Report - hCTNNB1/iso:1/Phos:7

PR:000037190 - http://purl.obolibrary.org/obo/PR_000037190
Ontology Information
PRO ID PR:000037190 Show OBO stanza / PAF
PRO name catenin beta-1 isoform 1 phosphorylated 7 (human)
Synonyms
PRO-short-label: hCTNNB1/iso:1/Phos:7
PRO-proteoform-std: UniProtKB:P35222-1, Ser-33/Ser-37, MOD:00046|Thr-41, MOD:00047
Definition A catenin beta-1 isoform 1 phosphorylated 7 in human. UniProtKB:P35222-1, Ser-33/Ser-37, MOD:00046|Thr-41, MOD:00047. [PMID:14500351, PRO:IC]
Comment Note: In vivo. Note: Found in colon cancer cells.
PRO Category organism-modification
Parent PR:000037189 catenin beta-1 isoform 1 phosphorylated 7
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000037190
hCTNNB1/iso:1/Phos:7
Ser-33/Ser-37, MOD:00046|Thr-41, MOD:00047
capable_of NOT GO:0005515 protein binding with PR:P12830 hCDH1 PMID:21152425
capable_of GO:0003713 transcription coactivator activity decreased relative to PR:000037185 hCTNNB1/iso:1/UnPhos:2 PMID:20419129
capable_of GO:0005515 protein binding decreased relative to PR:000037811 hCTNNB1/iso:1/UnPhos:5 with PR:Q9NQB0 hTCF7L2 PMID:23617586
capable_of GO:0005515 protein binding decreased relative to PR:000037811 hCTNNB1/iso:1/UnPhos:5 with PR:Q9UJU2 hLEF1 PMID:23617586
capable_of GO:0005515 protein binding decreased relative to PR:000037811 hCTNNB1/iso:1/UnPhos:5 with PR:P36402 hTCF7 PMID:23617586
capable_of GO:0005515 protein binding increased relative to PR:000037811 hCTNNB1/iso:1/UnPhos:5 with PR:Q9Y297 hBTRC PMID:21152425
capable_of GO:0005515 protein binding decreased relative to PR:000037811 hCTNNB1/iso:1/UnPhos:5 with PR:Q9HCS4 hTCF7L1 PMID:23617586
located_in GO:0005737 cytoplasm PMID:20419129
located_in GO:0005913 cell-cell adherens junction decreased relative to PR:000037811 hCTNNB1/iso:1/UnPhos:5 PMID:19667122
participates_in GO:0007155 cell adhesion decreased relative to PR:000037811 hCTNNB1/iso:1/UnPhos:5 PMID:19667122
participates_in GO:0034333 adherens junction assembly decreased relative to PR:000037811 hCTNNB1/iso:1/UnPhos:5 PMID:19667122
participates_in GO:0010631 epithelial cell migration PMID:21152425
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0007155 cell adhesion PR:000037190 hCTNNB1/iso:1/Phos:7
Ser-33/Ser-37, MOD:00046|Thr-41, MOD:00047
decreased relative to PR:000037811 hCTNNB1/iso:1/UnPhos:5
PMID:19667122
GO:0034333 adherens junction assembly PR:000037190 hCTNNB1/iso:1/Phos:7
Ser-33/Ser-37, MOD:00046|Thr-41, MOD:00047
decreased relative to PR:000037811 hCTNNB1/iso:1/UnPhos:5
PMID:19667122
GO:0010631 epithelial cell migration PR:000037190 hCTNNB1/iso:1/Phos:7
Ser-33/Ser-37, MOD:00046|Thr-41, MOD:00047
PMID:21152425
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005737 cytoplasm PR:000037190 hCTNNB1/iso:1/Phos:7
Ser-33/Ser-37, MOD:00046|Thr-41, MOD:00047
PMID:20419129
GO:0005913 cell-cell adherens junction PR:000037190 hCTNNB1/iso:1/Phos:7
Ser-33/Ser-37, MOD:00046|Thr-41, MOD:00047
decreased relative to PR:000037811 hCTNNB1/iso:1/UnPhos:5
PMID:19667122

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