back to PRO homepage
  Home |   Linked Open Data |   Browse |   Search |   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology Report - hMAPT/var:R406W

PR:000037552 - http://purl.obolibrary.org/obo/PR_000037552
Ontology Information
PRO ID PR:000037552 Show OBO stanza / PAF / GPI
PRO name microtubule-associated protein tau sequence variant R406W (human)
Synonyms
PRO-short-label: EXACT: hMAPT/var:R406W
PRO-proteoform-std: NARROW: UniProtKB:P10636-8, Arg-406, CHEBI:29954
Definition A microtubule-associated protein tau sequence variant (human) that has a Trp residue at the position equivalent to Arg-406 of the amino acid sequence represented by UniProtKB:P10636-8 (Tau-F; aka Arg-723 in PNS-Tau). Example: UniProtKB:P10636-8, Arg-406, CHEBI:29954. [Alzforum:KD, PMID:9382464, PRO:DAN]
Comment Requested by=Alzforum. Note: The position of variation given for UniProtKB_VAR:VAR_010353 is with respect to PNS-Tau numbering.
PRO Category organism-sequence
Parent PR:000028708 microtubule-associated protein tau sequence variant (human)
Taxon NCBITaxon:9606 Homo sapiens
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000037552
hMAPT/var:R406W
Arg-406, CHEBI:29954
associated_with_disease_progression DOID:9255 frontotemporal dementia PMID:10214944, PMID:11278002, PMID:11889249, PMID:14517953, PMID:9641683, PMID:9973279, UniProtKB_VAR:VAR_010353

top