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Protein Ontology Report - hTTK/pActloop

PR:000049844 - http://purl.obolibrary.org/obo/PR_000049844
Ontology Information
PRO ID PR:000049844 Show OBO stanza / PAF / GPI
PRO name TTK activation loop-phosphorylated form (human)
Synonyms
PRO-short-label: EXACT: hTTK/pActloop
PRO-proteoform-std: NARROW: UniProtKB:P33981-1, (Thr-675, MOD:00047 or Thr-676, MOD:00047)|Ser-677, MOD:00046
Definition A dual specificity protein kinase TTK (human) that has been phosphorylated on one of three sites within the activation loop, at positions equivalent to Thr-675 or Thr-676 or Ser-677 of the amino acid sequence represented by UniProtKB:P33981-1. Example: UniProtKB:P33981-1, (Thr-675, MOD:00047 or Thr-676, MOD:00047), Ser-677, MOD:00046. [PMID:17728254, PMID:18923149, PMID:1912069, PRO:KER]
Comment Evidence=(ECO:0000006, based on PMID:17728254). Evidence=(ECO:0000006, based on PMID:1912069). Evidence=(ECO:0000006, based on PMID:18923149). Kinase=("TTK"; PR:P33981; Thr-675). Kinase=("TTK"; PR:P33981; Thr-676). Kinase=("TTK"; PR:P33981; Ser-677).
PRO Category organism-modification
Parent PR:P33981 dual specificity protein kinase TTK (human)
Taxon NCBITaxon:9606 Homo sapiens
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000049844
hTTK/pActloop
acts_upstream_of_or_within GO:0046777 protein autophosphorylation PMID:18680479, PMID:19120698
enables GO:0004672 protein kinase activity PMID:18680479, PMID:19120698

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