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Protein Ontology Report - rep/Clv:nsp3 (SARS2)

PR:000050272 -
Ontology Information
PRO ID PR:000050272 Show OBO stanza
PRO name non-structural protein 3 (SARS-CoV-2)
PRO-short-label: rep/Clv:nsp3 (SARS2)
EXACT: PLpro (SARS-CoV-2); main proteinase (SARS-CoV-2); nsp3 (SARS-CoV-2); papain-like proteinase (SARS-CoV-2)
PRO-proteoform-ftid: PRO_0000449621; PRO_0000449637
PRO-proteoform-std: UniProtKB:P0DTC1, 819-2763; UniProtKB:P0DTD1, 819-2763
Definition A rep gene proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the autocatalytic action of PL-PRO proteinase (nsp3) when it cleaves the precursor rep gene translation product (SARS-CoV-2) between residues 818-819 and 2763-2764. [GenPept:YP_009725299, PRO:DAN, UniProtKB:P0DTC1, UniProtKB:P0DTD1]
Comment Note: 1945 aa protein. Unlike some other coronaviruses, SARS coronaviruses only encode a single papain-like proteinase, PLpro. [PMID:15564471]
PRO Category organism-modification
Parent PR:000050281 rep gene proteolytic cleavage product (SARS-CoV-2)
Taxon NCBITaxon:2697049 Severe acute respiratory syndrome coronavirus 2
Term Hierarchy Visualization DAG     OLS     Cytoscape

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Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment