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Protein Ontology Report - hDVL2

PR:O14641 - http://purl.obolibrary.org/obo/PR_O14641
This page represents a class of proteins encompassing all the protein products of the DVL2 gene in Homo sapiens.
Ontology Information
PRO ID PR:O14641 Show OBO stanza / PAF / GPI
PRO name segment polarity protein dishevelled homolog DVL-2 (human)
Synonyms
PRO-short-label: EXACT: hDVL2
Gene-based: RELATED: DVL2
Other: EXACT: DSH homolog 2 (human) | dishevelled-2 (human)
Definition A segment polarity protein dishevelled homolog DVL-2 that is encoded in the genome of human. [PMID:20823832, PRO:KER]
PRO Category organism-gene
Parent PR:000006767 segment polarity protein dishevelled homolog DVL-2
Gene Template HGNC:3086 DVL2
Taxon NCBITaxon:9606 Homo sapiens
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 1
organism-modification 4
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000035550
hDVL2/PhosRes-
acts_upstream_of_or_within GO:0031577 spindle checkpoint signaling PMID:20823832
located_in GO:0000776 kinetochore PMID:20823832
PR:000035549
hDVL2/Phos:1
Thr-206, MOD:00047
acts_upstream_of_or_within GO:0051294 establishment of spindle orientation increased relative to PR:000035550 hDVL2/PhosRes- PMID:20823832
acts_upstream_of_or_within GO:0031577 spindle checkpoint signaling PMID:20823832
PR:O14641
hDVL2
acts_upstream_of_or_within GO:0051310 metaphase plate congression PMID:20823832
acts_upstream_of_or_within GO:0031589 cell-substrate adhesion PMID:20823832
acts_upstream_of_or_within GO:0033674 positive regulation of kinase activity PMID:20823832
acts_upstream_of_or_within GO:0008608 attachment of spindle microtubules to kinetochore PMID:20823832
acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:20823832
acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:20823832
enables GO:0005515 protein binding with PR:P33981 hTTK PMID:20823832
enables GO:0005515 protein binding with PR:P53350 hPLK1 PMID:20823832
enables GO:0005515 protein binding with PR:P25054 hAPC PMID:20823832
located_in GO:0000922 spindle pole PMID:20823832
located_in GO:0000776 kinetochore PMID:20823832
located_in GO:0005819 spindle PMID:20823832
located_in GO:0032154 cleavage furrow PMID:20823832
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005819 spindle PR:O14641 hDVL2

PMID:20823832
GO:0000922 spindle pole PR:O14641 hDVL2

PMID:20823832
GO:0000776 kinetochore PR:000035550 hDVL2/PhosRes-

PMID:20823832
PR:O14641 hDVL2

PMID:20823832
GO:0032154 cleavage furrow PR:O14641 hDVL2

PMID:20823832

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