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Protein Ontology Report - hSMAD7

PR:O15105 - http://purl.obolibrary.org/obo/PR_O15105
This page represents a class of proteins encompassing all the protein products of the SMAD7 gene in human.
Ontology Information
PRO ID PR:O15105 Show OBO stanza / PAF
PRO name mothers against decapentaplegic homolog 7 (human)
Synonyms
PRO-short-label: hSMAD7
EXACT: MAD homolog 7 (human); MAD homolog 8 (human); SMAD 7 (human); SMAD family member 7 (human); Smad7 (human); mothers against DPP homolog 7 (human); mothers against DPP homolog 8 (human); mothers against decapentaplegic homolog 8 (human)
Gene-based: MADH7; MADH8; SMAD7
Definition A smad7 that is encoded in the genome of human.
PRO Category organism-gene
Parent PR:000000374 smad7
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 3
organism-modification 2
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:O15105-1
hSMAD7/iso:1
capable_of GO:0005515 protein binding PMID:9256479
capable_of GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity PMID:9215638
located_in GO:0005634 nucleus PMID:11278814
participates_in GO:0006950 response to stress PMID:9256479
participates_in GO:0007179 transforming growth factor beta receptor signaling pathway PMID:10823886, PMID:9215638
PR:000036565
hSMAD7/iso:1/Ac:1
Lys-64/Lys-70, MOD:00723
capable_of GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity PMID:12408818
located_in GO:0005634 nucleus PMID:11278814
participates_in GO:0007179 transforming growth factor beta receptor signaling pathway PMID:12408818
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0006950 response to stress PR:O15105-1 hSMAD7/iso:1

PMID:9256479
GO:0007179 transforming growth factor beta receptor signaling pathway PR:000036565 hSMAD7/iso:1/Ac:1
Lys-64/Lys-70, MOD:00723
PMID:12408818
PR:O15105-1 hSMAD7/iso:1

PMID:10823886, PMID:9215638
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:000036565 hSMAD7/iso:1/Ac:1
Lys-64/Lys-70, MOD:00723
PMID:11278814
PR:O15105-1 hSMAD7/iso:1

PMID:11278814

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