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Protein Ontology Report - mSPTLC1

PR:O35704 - http://purl.obolibrary.org/obo/PR_O35704
This page represents a class of proteins encompassing all the protein products of the Sptlc1 gene in Mus musculus.
Ontology Information
PRO ID PR:O35704 Show OBO stanza / PAF / GPI
PRO name serine palmitoyltransferase 1 (mouse)
Synonyms
PRO-short-label: EXACT: mSPTLC1
Gene-based: RELATED: Lcb1 | Sptlc1
Other: EXACT: LCB 1 (mouse) | SPT 1 (mouse) | SPT1 (mouse) | long chain base biosynthesis protein 1 (mouse) | serine-palmitoyl-CoA transferase 1 (mouse)
Definition A serine palmitoyltransferase 1 that is encoded in the genome of mouse. [OMA:O35704, PRO:HJD]
PRO Category organism-gene
Parent PR:000015596 serine palmitoyltransferase 1
Gene Template MGI:1099431 Sptlc1
Taxon NCBITaxon:10090 Mus musculus
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 1
organism-modification 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

mSPTLC1 forms found in complexes
mSPTLC1 Component Complexes
PR:O35704 mSPTLC1 PR:000025761 serine palmitoyltransferase complex (mouse)
PR:O35704 mSPTLC1 PR:000025762 serine palmitoyltransferase complex A (mouse)

Functional Annotation
PRO Term GO Annotation Evidence
PR:O35704
mSPTLC1
acts_upstream_of_or_within GO:0006686 sphingomyelin biosynthetic process PMID:16216550
acts_upstream_of_or_within GO:0046511 sphinganine biosynthetic process PMID:19416652
acts_upstream_of_or_within GO:0046512 sphingosine biosynthetic process PMID:16216550
acts_upstream_of_or_within GO:0046513 ceramide biosynthetic process PMID:16216550
PR:O35704-1
mSPTLC1/iso:1
enables NOT GO:0004758 serine C-palmitoyltransferase activity PMID:9363775
enables GO:0005515 protein binding with PR:P41233 mABCA1 PMID:18484747

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