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Protein Ontology Report - hBUB3

PR:O43684 - http://purl.obolibrary.org/obo/PR_O43684
This page represents a class of proteins encompassing all the protein products of the BUB3 gene in human.
Ontology Information
PRO ID PR:O43684 Show OBO stanza / PAF
PRO name mitotic checkpoint protein BUB3 (human)
Synonyms
PRO-short-label: hBUB3
Gene-based: BUB3
Definition A mitotic checkpoint protein BUB3 that is encoded in the genome of human. [PRO:DNx, UniProtKB:O43684]
PRO Category organism-gene
Parent PR:000004856 mitotic checkpoint protein BUB3
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 2
organism-modification 3
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

hBUB3 forms found in complexes
hBUB3 Component Complexes
PR:O43684 hBUB3 PR:000035576 BUB1:BUB3:APC complex (human)
PR:O43684 hBUB3 PR:000035567 BUB1:BUB3:MAD1L1 complex (human)
PR:O43684 hBUB3 PR:000035511 BUB1B:BUB3:MAD2:CDC20 complex (human)
PR:O43684 hBUB3 PR:000035563 BUB1B:BUB3 complex (human)
PR:O43684 hBUB3 PR:000035564 BUB1:BUB3 complex (human)

Functional Annotation
PRO Term GO Annotation Evidence
PR:000035437
hBUB3/Phos:1
Ser-18, MOD:00046
participates_in GO:0012501 programmed cell death increased relative to PR:000035454 hBUB3/PhosRes- PMID:20057499
PR:O43684
hBUB3
capable_of GO:0005515 protein binding with PR:Q9Y6D9 hMAD1L1 PMID:10198256
capable_of GO:0005515 protein binding with PR:P25054 hAPC BioGRID:BG-302961
capable_of GO:0005515 protein binding with PR:O60566 hBUB1B PMID:17785528
capable_of GO:0005515 protein binding with PR:O43683 hBUB1 PMID:10198256
capable_of GO:0005515 protein binding with PR:O15350-3 hTP73/iso:3 PMID:20057499
capable_of GO:0005515 protein binding with PR:O15350-1 hTP73/iso:1 PMID:20057499
capable_of GO:0005515 protein binding with PR:Q13257 hMAD2L1 BioGRID:BG-718926
capable_of GO:0005515 protein binding with PR:O15350-5 hTP73/iso:5 PMID:20057499
capable_of GO:0005515 protein binding with PR:O15350-2 hTP73/iso:2 PMID:20057499
capable_of GO:0005515 protein binding with PR:Q12834 hCDC20 BioGRID:BG-561804, MINT:MINT-8183848
located_in GO:0000776 kinetochore PMID:11283619
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0012501 programmed cell death PR:000035437 hBUB3/Phos:1
Ser-18, MOD:00046
increased relative to PR:000035454 hBUB3/PhosRes-
PMID:20057499
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0000776 kinetochore PR:O43684 hBUB3

PMID:11283619

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