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Protein Ontology Report - hCD4

PR:P01730 - http://purl.obolibrary.org/obo/PR_P01730
This page represents a class of proteins encompassing all the protein products of the CD4 gene in human.
Ontology Information
PRO ID PR:P01730 Show OBO stanza / PAF
PRO name T-cell surface glycoprotein CD4 (human)
Synonyms
PRO-short-label: hCD4
EXACT: CD4 (human); T-cell surface antigen T4/Leu-3 (human)
Gene-based: CD4
Definition A CD4 molecule that is encoded in the genome of human. [PRO:DNx, UniProtKB:P01730]
PRO Category organism-gene
Parent PR:000001004 CD4 molecule
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 1
organism-modification 2
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

hCD4 forms found in complexes
hCD4 Component Complexes
PR:000028418 hCD4/SigPep- PR:000028449 CD4:Lck complex (human)

Functional Annotation
PRO Term GO Annotation Evidence
PR:P01730
hCD4
capable_of GO:0005515 protein binding with PR:P05879 env (HIV-1 M:B_CDC-451) PMID:9269777
participates_in GO:0090630 activation of GTPase activity PMID:9269777
PR:000036630
hCD4/iso:1/Phos:1
capable_of GO:0001618 virus receptor activity PMID:3259291
capable_of GO:0005515 protein binding with PR:000003229 env/Clv:gp120/GlycoRes+ PMID:3259291
PR:000001004
CD4
has_part Pfam:PF05790 Immunoglobulin C2-set domain PIRSF:PIRSF001977
has_part Pfam:PF00047 Immunoglobulin domain PIRSF:PIRSF001977
has_part Pfam:PF09191 CD4, extracellular PIRSF:PIRSF001977
has_part Pfam:PF07686 Immunoglobulin V-set domain PIRSF:PIRSF001977
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0090630 activation of GTPase activity PR:P01730 hCD4

PMID:9269777

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