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Protein Ontology Report - hSKI

PR:P12755 - http://purl.obolibrary.org/obo/PR_P12755
This page represents a class of proteins encompassing all the protein products of the SKI gene in human.
Ontology Information
PRO ID PR:P12755 Show OBO stanza / PAF
PRO name ski oncogene (human)
Synonyms
PRO-short-label: hSKI
EXACT: proto-oncogene c-Ski (human)
Gene-based: SKI
Definition A ski oncogene that is encoded in the genome of human. [PRO:CNA, UniProtKB:P12755]
PRO Category organism-gene
Parent PR:000003214 ski oncogene
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 1
organism-modification 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

hSKI forms found in complexes
hSKI Component Complexes
PR:P12755-1 hSKI/iso:1 PR:000025951 smad2-smad4-ski protein complex 1 (human)
PR:P12755-1 hSKI/iso:1 PR:000025952 smad2-smad4-ski protein complex 2 (human)

Functional Annotation
PRO Term GO Annotation Evidence
PR:000025952
smad2-smad4-ski protein complex 2 (human)
located_in GO:0005737 cytoplasm PMID:12732634
participates_in GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway PMID:12732634
PR:000025951
smad2-smad4-ski protein complex 1 (human)
located_in GO:0005634 nucleus PMID:10485843
participates_in GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway PMID:10485843
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway PR:000025951 smad2-smad4-ski protein complex 1 (human)

PMID:10485843
PR:000025952 smad2-smad4-ski protein complex 2 (human)

PMID:12732634
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:000025951 smad2-smad4-ski protein complex 1 (human)

PMID:10485843
GO:0005737 cytoplasm PR:000025952 smad2-smad4-ski protein complex 2 (human)

PMID:12732634

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