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Protein Ontology Report - hPML/iso:5

PR:P29590-5 - http://purl.obolibrary.org/obo/PR_P29590-5
Ontology Information
PRO ID PR:P29590-5 Show OBO stanza / PAF
PRO name transcription factor PML isoform 5 (human)
Alternate ID PR:000026519
Synonyms
PRO-short-label: hPML/iso:5
Definition A transcription factor PML isoform 5 that is encoded in the genome of human. [PMID:15195100]
PRO Category organism-sequence
Parent PR:000026518 transcription factor PML isoform 5
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:P29590-5
hPML/iso:5
capable_of GO:0005515 protein binding with PR:Q13547 hHDAC1 PMID:11259576
capable_of GO:0003713 transcription coactivator activity PMID:11080164
capable_of GO:0005515 protein binding with PR:O15379 hHDAC3 PMID:11259576
capable_of GO:0005515 protein binding with PR:Q92769 hHDAC2 PMID:11259576
capable_of GO:0005515 protein binding with PR:P04637 hTP53 PMID:11080164
capable_of GO:0005515 protein binding with PR:Q00987 hMDM2 PMID:12915590
capable_of GO:0005515 protein binding with PR:Q05516 hZBTB16 PMID:9294197
capable_of GO:0005515 protein binding with PR:Q00987 hMDM2 PMID:12915590
capable_of GO:0005515 protein binding with PR:P06400 hRB1 PMID:9448006
capable_of GO:0005515 protein binding with PR:Q05516 hZBTB16 PMID:9294197
capable_of GO:0005515 protein binding with PR:Q92547 hTOPBP1 PMID:12773567
capable_of GO:0005515 protein binding with PR:P62913 hRPL11 PMID:15195100
capable_of GO:0005515 protein binding with PR:O96017 hCHEK2 PMID:12402044
capable_of GO:0003713 transcription coactivator activity PMID:15626733
located_in GO:0005737 cytoplasm PMID:16778193
located_in GO:0016605 PML body PMID:9448006
located_in GO:0016363 nuclear matrix PMID:11080164
located_in GO:0005730 nucleolus PMID:16778193
participates_in GO:0045892 negative regulation of transcription, DNA-templated PMID:9448006
participates_in GO:0007050 cell cycle arrest PMID:12773567
participates_in GO:0031065 positive regulation of histone deacetylation PMID:11259576
participates_in GO:0006605 protein targeting PMID:15195100
participates_in GO:0006915 apoptotic process PMID:11080164
participates_in GO:0006605 protein targeting PMID:11080164
participates_in GO:0032938 negative regulation of translation in response to oxidative stress PMID:16915281
participates_in GO:0050821 protein stabilization PMID:12773567
participates_in GO:0030308 negative regulation of cell growth PMID:9448006
participates_in GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage PMID:12402044
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0007050 cell cycle arrest PR:P29590-5 hPML/iso:5

PMID:12773567
GO:0032938 negative regulation of translation in response to oxidative stress PR:P29590-5 hPML/iso:5

PMID:16915281
GO:0031065 positive regulation of histone deacetylation PR:P29590-5 hPML/iso:5

PMID:11259576
GO:0006605 protein targeting PR:P29590-5 hPML/iso:5

PMID:15195100
PR:P29590-5 hPML/iso:5

PMID:11080164
GO:0030308 negative regulation of cell growth PR:P29590-5 hPML/iso:5

PMID:9448006
GO:0045892 negative regulation of transcription, DNA-templated PR:P29590-5 hPML/iso:5

PMID:9448006
GO:0006915 apoptotic process PR:P29590-5 hPML/iso:5

PMID:11080164
GO:0050821 protein stabilization PR:P29590-5 hPML/iso:5

PMID:12773567
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage PR:P29590-5 hPML/iso:5

PMID:12402044
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0016363 nuclear matrix PR:P29590-5 hPML/iso:5

PMID:11080164
GO:0016605 PML body PR:P29590-5 hPML/iso:5

PMID:9448006
GO:0005737 cytoplasm PR:P29590-5 hPML/iso:5

PMID:16778193
GO:0005730 nucleolus PR:P29590-5 hPML/iso:5

PMID:16778193

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