Protein Ontology Report - hTTK PR:P33981 - http://purl.obolibrary.org/obo/PR_P33981

This page represents a class of proteins encompassing all the protein products of the TTK gene in Homo sapiens.

Ontology Information
PRO ID	PR:P33981 Show OBO stanza / PAF / GPI
PRO name	dual specificity protein kinase TTK (human)
Synonyms	PRO-short-label: EXACT: hTTK Gene-based: RELATED: MPS1 | MPS1L1 | TTK Other: EXACT: PYT (human) | phosphotyrosine picked threonine-protein kinase (human)
Definition	A dual specificity protein kinase TTK that is encoded in the genome of human. [PMID:20823832, PRO:KER]
PRO Category	organism-gene
Parent	PR:000016787 dual specificity protein kinase TTK
Gene Template	HGNC:12401 TTK
Taxon	NCBITaxon:9606 Homo sapiens
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 2 organism-modification 3
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	DTO:03100547, UniProtKB:P33981

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence organism-modification
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:P33981 hTTK acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:20624902 acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:20624902, PMID:22732840 acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:22732840 acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:20624902 acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:20624902 acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:20624902 acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:20624902 acts_upstream_of_or_within GO:0032092 positive regulation of protein binding PMID:20624902 acts_upstream_of_or_within GO:0032092 positive regulation of protein binding PMID:22660415 acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:20624902, PMID:22732840 acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:20624902 acts_upstream_of_or_within NOT GO:0034501 protein localization to kinetochore PMID:20624902 acts_upstream_of_or_within NOT GO:0034501 protein localization to kinetochore PMID:20624902 acts_upstream_of_or_within NOT GO:0034501 protein localization to kinetochore PMID:20624902 acts_upstream_of_or_within GO:0045841 negative regulation of mitotic metaphase/anaphase transition PMID:20624902 acts_upstream_of_or_within GO:0051310 metaphase plate congression PMID:20624902, PMID:22732840 acts_upstream_of_or_within GO:0031577 spindle checkpoint signaling PMID:20624902 enables GO:0005515 protein binding with PR:Q12834 hCDC20 BioGRID:BG-590746 located_in GO:0000776 kinetochore PMID:20624902 PR:000045754 hTTK/Phos:1 Thr-676, MOD:00047 acts_upstream_of_or_within GO:0051298 centrosome duplication PMID:17728254 acts_upstream_of_or_within GO:0071174 mitotic spindle checkpoint signaling PMID:18083840 acts_upstream_of_or_within GO:0046777 protein autophosphorylation PMID:18680479, PMID:19120698 enables GO:0004672 protein kinase activity PMID:18680479 PR:000049845 hTTK/p(Act-loop_P+1-loop) enables GO:0004672 protein kinase activity PMID:19120698 PR:000049844 hTTK/pActloop acts_upstream_of_or_within GO:0046777 protein autophosphorylation PMID:18680479, PMID:19120698 enables GO:0004672 protein kinase activity PMID:18680479, PMID:19120698 Cellular Location GO Term Protein Forms & Complexes Evidence GO:0000776 kinetochore PR:P33981 hTTK PMID:20624902

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