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Protein Ontology Report - hRBX1

PR:P62877 - http://purl.obolibrary.org/obo/PR_P62877
This page represents a class of proteins encompassing all the protein products of the RBX1 gene in human.
Ontology Information
PRO ID PR:P62877 Show OBO stanza / PAF
PRO name E3 ubiquitin-protein ligase RBX1 (human)
Synonyms
PRO-short-label: hRBX1
EXACT: E3 ubiquitin-protein transferase RBX1 (human); RING finger protein 75 (human); RING-box protein 1 (human); Rbx1 (human); protein ZYP (human); regulator of cullins 1 (human)
Gene-based: RBX1; RNF75; ROC1
RELATED: ROC1 (human)
Definition An E3 ubiquitin-protein ligase RBX1 that is encoded in the genome of human. [PRO:CNA, UniProtKB:P62877]
PRO Category organism-gene
Parent PR:000000043 E3 ubiquitin-protein ligase RBX1
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 1
organism-modification 1
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

hRBX1 forms found in complexes
hRBX1 Component Complexes
PR:000026756 hRBX1/InitMet- PR:000037513 FBXO4:CRYAB:Skp1:Cul1:Rbx1 complex (human)
PR:000026756 hRBX1/InitMet- PR:000026771 SCF beta-TrCP complex (human)

Functional Annotation
PRO Term GO Annotation Evidence
PR:000000043
RBX1
part_of GO:0019005 SCF ubiquitin ligase complex PIRSF:PIRSF500724
participates_in GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process PIRSF:PIRSF500724
PR:P62877-1
hRBX1/iso:1
capable_of GO:0005515 protein binding with PR:Q13616-1 hCUL1/iso:1 PMID:11961546
capable_of GO:0005515 protein binding with PR:Q9EQW6 mOLIG2 PMID:11027288
part_of GO:0000151 ubiquitin ligase complex PMID:17217622
part_of GO:0031462 Cul2-RING ubiquitin ligase complex PMID:15966899
part_of GO:0019005 SCF ubiquitin ligase complex PMID:15966899
part_of GO:0000151 ubiquitin ligase complex PMID:16325183
participates_in GO:0006606 protein import into nucleus PMID:11027288
participates_in GO:0006511 ubiquitin-dependent protein catabolic process PMID:10230407
participates_in GO:0045116 protein neddylation PMID:15966899
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0006511 ubiquitin-dependent protein catabolic process PR:P62877-1 hRBX1/iso:1

PMID:10230407
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process PR:000000043 RBX1

PIRSF:PIRSF500724
GO:0045116 protein neddylation PR:P62877-1 hRBX1/iso:1

PMID:15966899
GO:0006606 protein import into nucleus PR:P62877-1 hRBX1/iso:1

PMID:11027288

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