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Protein Ontology Report - hACVR1

PR:Q04771 - http://purl.obolibrary.org/obo/PR_Q04771
This page represents a class of proteins encompassing all the protein products of the ACVR1 gene in human.
Ontology Information
PRO ID PR:Q04771 Show OBO stanza / PAF
PRO name activin receptor type-1 (human)
Synonyms
PRO-short-label: hACVR1
BROAD: TGF-B superfamily receptor type I (human); TSR-I (human)
EXACT: ACTR-I (human); ALK-2 (human); SKR1 (human); activin receptor type I (human); activin receptor-like kinase 2 (human); serine/threonine-protein kinase receptor R1 (human)
Gene-based: ACVR1; ACVRLK2
Definition An activin receptor type-1 that is encoded in the genome of human. [PRO:CNA, UniProtKB:Q04771]
Comment Requested by=PubChem.
PRO Category organism-gene
Parent PR:000000067 activin receptor type-1
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 2
organism-modification 1
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000000200
hACVR1/var:R206H
Arg-206, CHEBI:29979
associated_with_disease_progression DOID:13374 fibrodysplasia ossificans progressiva PMID:8397373
located_in GO:0005887 integral component of plasma membrane PMID:8397373
PR:000036435
hACVR1/iso:1/SigPep-/Phos:1
capable_of GO:0004675 transmembrane receptor protein serine/threonine kinase activity PMID:8389764
capable_of GO:0048185 activin binding PMID:8242742
located_in GO:0005887 integral component of plasma membrane PMID:8242742, PMID:8397373
part_of GO:0048179 activin receptor complex PMID:8242742
participates_in GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway PMID:8242742, PMID:8389764
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway PR:000036435 hACVR1/iso:1/SigPep-/Phos:1

PMID:8242742, PMID:8389764
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005887 integral component of plasma membrane PR:000000200 hACVR1/var:R206H
Arg-206, CHEBI:29979
PMID:8397373
PR:000036435 hACVR1/iso:1/SigPep-/Phos:1

PMID:8242742, PMID:8397373

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