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Protein Ontology Report - mTICAM2

PR:Q8BJQ4 - http://purl.obolibrary.org/obo/PR_Q8BJQ4
This page represents a class of proteins encompassing all the protein products of the Ticam2 gene in mouse.
Ontology Information
PRO ID PR:Q8BJQ4 Show OBO stanza / PAF
PRO name TIR domain-containing adapter molecule 2 (mouse)
Synonyms
PRO-short-label: mTICAM2
EXACT: TICAM-2 (mouse); TRIF-related adapter molecule (mouse); Toll/interleukin-1 receptor domain-containing protein (mouse)
Gene-based: Ticam2; Tirp; Tram
Definition A TIR domain-containing adapter molecule 2 that is encoded in the genome of mouse. [PRO:CNA]
PRO Category organism-gene
Parent PR:000001750 TIR domain-containing adapter molecule 2
Gene Template MGI:3040056 Ticam2
Taxon NCBITaxon:10090 Mus musculus
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 1
organism-modification 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

mTICAM2 forms found in complexes
mTICAM2 Component Complexes
PR:Q8BJQ4 mTICAM2 PR:000036109 pel1:K63-poly-Ub-rip1:traf6:ticam1:ticam2:activated TLR4 complex (mouse)
PR:Q8BJQ4 mTICAM2 PR:000036105 pel1:rip1:traf6:ticam1:ticam2:activated TLR4 complex (mouse)
PR:Q8BJQ4 mTICAM2 PR:000036101 rip1:traf6:ticam1:ticam2:activated TLR4 complex (mouse)
PR:Q8BJQ4 mTICAM2 PR:000036099 ikke:K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex (mouse)
PR:Q8BJQ4 mTICAM2 PR:000036097 tbk1:K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex (mouse)
PR:Q8BJQ4 mTICAM2 PR:000035710 traf6:ticam1:ticam2:activated TLR4 complex (mouse)
PR:Q8BJQ4 mTICAM2 PR:000036093 tbk1:K63-poly-Ub-tank:Ikke:traf3:ticam1:ticam2:activated TLR4 complex (mouse)
PR:Q8BJQ4 mTICAM2 PR:000036090 tbk1:tank:ikke:traf3:ticam1:ticam2:activated TLR4 complex (mouse)
PR:Q8BJQ4 mTICAM2 PR:000028683 traf3:ticam1:ticam2:activated TLR4 complex (mouse)
PR:Q8BJQ4 mTICAM2 PR:000027207 ticam1:ticam2:activated TLR4 complex (mouse)
PR:Q8BJQ4 mTICAM2 PR:000027204 ticam2:activated TLR4 complex (mouse)
PR:Q8BJQ4 mTICAM2 PR:000036095 K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex (mouse)

Functional Annotation
PRO Term GO Annotation Evidence
PR:000035710
traf6:ticam1:ticam2:activated TLR4 complex (mouse)
participates_in GO:0002756 MyD88-independent toll-like receptor signaling pathway PMID:14530355
PR:000028683
traf3:ticam1:ticam2:activated TLR4 complex (mouse)
participates_in GO:0034142 toll-like receptor 4 signaling pathway PMID:16306937
participates_in GO:0002756 MyD88-independent toll-like receptor signaling pathway PMID:16306937
PR:000036101
rip1:traf6:ticam1:ticam2:activated TLR4 complex (mouse)
participates_in GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809
PR:000027207
ticam1:ticam2:activated TLR4 complex (mouse)
located_in GO:0010008 endosome membrane PMID:18222170
participates_in GO:0002756 MyD88-independent toll-like receptor signaling pathway PMID:18222170
participates_in GO:0034142 toll-like receptor 4 signaling pathway PMID:18222170
PR:000027204
ticam2:activated TLR4 complex (mouse)
located_in GO:0010008 endosome membrane PMID:18222170
participates_in GO:0002756 MyD88-independent toll-like receptor signaling pathway PMID:18222170
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0002756 MyD88-independent toll-like receptor signaling pathway PR:000027204 ticam2:activated TLR4 complex (mouse)

PMID:18222170
PR:000027207 ticam1:ticam2:activated TLR4 complex (mouse)

PMID:18222170
PR:000028683 traf3:ticam1:ticam2:activated TLR4 complex (mouse)

PMID:16306937
PR:000035710 traf6:ticam1:ticam2:activated TLR4 complex (mouse)

PMID:14530355
PR:000036101 rip1:traf6:ticam1:ticam2:activated TLR4 complex (mouse)

Reactome:REACT_6809
GO:0034142 toll-like receptor 4 signaling pathway PR:000027207 ticam1:ticam2:activated TLR4 complex (mouse)

PMID:18222170
PR:000028683 traf3:ticam1:ticam2:activated TLR4 complex (mouse)

PMID:16306937
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0010008 endosome membrane PR:000027204 ticam2:activated TLR4 complex (mouse)

PMID:18222170
PR:000027207 ticam1:ticam2:activated TLR4 complex (mouse)

PMID:18222170

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