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Protein Ontology Report - mSIRT3

PR:Q8R104 - http://purl.obolibrary.org/obo/PR_Q8R104
This page represents a class of proteins encompassing all the protein products of the Sirt3 gene in mouse.
Ontology Information
PRO ID PR:Q8R104 Show OBO stanza / PAF
PRO name NAD-dependent protein deacetylase sirtuin-3 (mouse)
Synonyms
PRO-short-label: mSIRT3
EXACT: SIR2-like protein 3 (mouse); mSIR2L3; regulatory protein SIR2 homolog 3 (mouse)
Gene-based: Sir2l3; Sirt3
Definition An NAD-dependent protein deacetylase sirtuin-3, mitochondrial that is encoded in the genome of mouse. [PRO:DNx]
PRO Category organism-gene
Parent PR:000029756 NAD-dependent protein deacetylase sirtuin-3, mitochondrial
Gene Template MGI:1927665 Sirt3
Taxon NCBITaxon:10090 Mus musculus
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 2
organism-modification 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:Q8R104-1
mSIRT3/iso:1
capable_of GO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific) MGI:4830236, PMID:19241369
located_in GO:0005739 mitochondrion MGI:4830236, PMID:19241369
participates_in GO:0006476 protein deacetylation MGI:4830236, PMID:19241369
PR:Q8R104-2
mSIRT3/iso:2
capable_of NOT GO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific) MGI:1926994, PMID:11056054
located_in GO:0005737 cytoplasm MGI:1926994, PMID:11056054
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0006476 protein deacetylation PR:Q8R104-1 mSIRT3/iso:1

MGI:4830236, PMID:19241369
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005737 cytoplasm PR:Q8R104-2 mSIRT3/iso:2

MGI:1926994, PMID:11056054
GO:0005739 mitochondrion PR:Q8R104-1 mSIRT3/iso:1

MGI:4830236, PMID:19241369

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