Protein Ontology Report - hHCN4 PR:Q9Y3Q4 - http://purl.obolibrary.org/obo/PR_Q9Y3Q4

This page represents a class of proteins encompassing all the protein products of the HCN4 gene in Homo sapiens.

Ontology Information
PRO ID	PR:Q9Y3Q4 Show OBO stanza / PAF / GPI
PRO name	potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (human)
Synonyms	PRO-short-label: EXACT: hHCN4 Gene-based: RELATED: HCN4
Definition	A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 that is encoded in the genome of human. [PRO:CNA, UniProtKB:Q9Y3Q4]
PRO Category	organism-gene
Parent	PR:000000708 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Gene Template	HGNC:16882 HCN4
Taxon	NCBITaxon:9606 Homo sapiens
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 3 organism-modification 0
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	DTO:01100147, Reactome:R-HSA-977498, UniProtKB:Q9Y3Q4

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:Q9Y3Q4-1 hHCN4/iso:1 acts_upstream_of_or_within GO:0006936 muscle contraction PMID:10228147 acts_upstream_of_or_within GO:0006812 cation transport PMID:10228147 enables GO:0005261 cation channel activity PMID:10228147 PR:000000759 hHCN4/var:D553N Asp-553, CHEBI:50347 associated_with_disease_progression DOID:13884 sick sinus syndrome PMID:15123648 located_in NOT GO:0005886 plasma membrane PMID:15123648 PR:000000760 hHCN4/var:S672R Ser-672, CHEBI:29952 associated_with_disease_progression DOID:13884 sick sinus syndrome PMID:16407510 enables GO:0005222 intracellular cAMP-activated cation channel activity PMID:16407510 enables GO:0022843 voltage-gated cation channel activity PMID:16407510 Cellular Location GO Term Protein Forms & Complexes Evidence NOT GO:0005886 plasma membrane PR:000000759 hHCN4/var:D553N Asp-553, CHEBI:50347 PMID:15123648

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