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Protein Ontology Report - hRIPK3

PR:Q9Y572 - http://purl.obolibrary.org/obo/PR_Q9Y572
This page represents a class of proteins encompassing all the protein products of the RIPK3 gene in human.
Ontology Information
PRO ID PR:Q9Y572 Show OBO stanza / PAF
PRO name receptor-interacting serine/threonine-protein kinase 3 (human)
Synonyms
PRO-short-label: hRIPK3
EXACT: RIP-3 (human); RIP-like protein kinase 3 (human); receptor-interacting protein 3 (human)
Gene-based: RIP3; RIPK3
Definition A receptor-interacting serine/threonine-protein kinase 3 that is encoded in the genome of human. [PRO:CNA, Reactome:R-HSA-450328]
PRO Category organism-gene
Parent PR:000014024 receptor-interacting serine/threonine-protein kinase 3
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 3
organism-modification 1
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

hRIPK3 forms found in complexes
hRIPK3 Component Complexes
PR:Q9Y572 hRIPK3 PR:000036058 rip1:rip3:ticam1:ticam2:activated TLR4 complex (human)
PR:Q9Y572 hRIPK3 PR:000037332 rip3:ticam1:activated TLR3 complex (human)
PR:Q9Y572 hRIPK3 PR:000037336 rip1:rip3:ticam1:activated TLR3 complex (human)
PR:Q9Y572 hRIPK3 PR:000036056 rip3:ticam1:ticam2:activated TLR4 complex (human)

Functional Annotation
PRO Term GO Annotation Evidence
PR:000036056
rip3:ticam1:ticam2:activated TLR4 complex (human)
located_in GO:0010008 endosome membrane Reactome:REACT_152149
participates_in GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809
PR:000036058
rip1:rip3:ticam1:ticam2:activated TLR4 complex (human)
located_in GO:0010008 endosome membrane Reactome:REACT_151344
participates_in GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809
PR:000037332
rip3:ticam1:activated TLR3 complex (human)
located_in GO:0010008 endosome membrane Reactome:REACT_6783
participates_in GO:0034138 toll-like receptor 3 signaling pathway Reactome:REACT_6783
participates_in GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6783
PR:Q9Y572
hRIPK3
located_in GO:0005737 cytoplasm Reactome:REACT_22021
PR:000037336
rip1:rip3:ticam1:activated TLR3 complex (human)
located_in GO:0010008 endosome membrane Reactome:REACT_6783
participates_in GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6783
participates_in GO:0034138 toll-like receptor 3 signaling pathway Reactome:REACT_6783
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0002756 MyD88-independent toll-like receptor signaling pathway PR:000036056 rip3:ticam1:ticam2:activated TLR4 complex (human)

Reactome:REACT_6809
PR:000036058 rip1:rip3:ticam1:ticam2:activated TLR4 complex (human)

Reactome:REACT_6809
PR:000037332 rip3:ticam1:activated TLR3 complex (human)

Reactome:REACT_6783
PR:000037336 rip1:rip3:ticam1:activated TLR3 complex (human)

Reactome:REACT_6783
GO:0034138 toll-like receptor 3 signaling pathway PR:000037332 rip3:ticam1:activated TLR3 complex (human)

Reactome:REACT_6783
PR:000037336 rip1:rip3:ticam1:activated TLR3 complex (human)

Reactome:REACT_6783
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005737 cytoplasm PR:Q9Y572 hRIPK3

Reactome:REACT_22021
GO:0010008 endosome membrane PR:000036056 rip3:ticam1:ticam2:activated TLR4 complex (human)

Reactome:REACT_152149
PR:000036058 rip1:rip3:ticam1:ticam2:activated TLR4 complex (human)

Reactome:REACT_151344
PR:000037332 rip3:ticam1:activated TLR3 complex (human)

Reactome:REACT_6783
PR:000037336 rip1:rip3:ticam1:activated TLR3 complex (human)

Reactome:REACT_6783

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